Successful treatment of primary donor-derived human herpesvirus-8 infection and hepatic Kaposi Sarcoma in an adult liver transplant recipient

Transplant Infectious Disease : an Official Journal of the Transplantation Society
Whitney FuPeter S Yoo

Abstract

Kaposi sarcoma (KS) may rarely occur in transplant recipients through primary human herpesvirus-8 (HHV-8) infection from a seropositive donor. This report describes a patient who developed hepatic KS after receiving a split liver transplant from an HHV-8-positive donor. The recipient was treated with liposomal doxorubicin after reduction in immunosuppression led to acute cellular rejection. This treatment achieved regression of KS while preserving allograft function, demonstrating a successful therapeutic strategy for this malignancy.

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Citations

Mar 8, 2019·Pediatric Transplantation·Karen E OcwiejaTanvi S Sharma
Mar 8, 2019·Clinical Transplantation·Rebecca Pellett MadanUNKNOWN AST Infectious Diseases Community of Practice
Jun 21, 2019·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Vinay NairErnesto Molmenti
Aug 24, 2018·Drug and Therapeutics Bulletin
Jul 11, 2019·Current Opinion in Organ Transplantation·Deepa D Nanayakkara, Joanna Schaenman

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