PMID: 30005104Jul 14, 2018Paper

Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib

Journal of Drugs in Dermatology : JDD
Michelle W ChengCarolyn Goh

Abstract

Alopecia areata is an autoimmune disease involving the hair follicle with a chronic, relapsing course. Tofacitinib is Janus kinase inhibitor approved for treatment of rheumatoid arthritis that has been shown to be effective in treatment of alopecia areata. We present a case series of 11 patients with severe alopecia areata on longstanding, regular to high dose oral tofacitinib with marked hair regrowth. Additionally, we present a case of moderate to severe alopecia areata successfully treated with topical tofacitinib cream. J Drugs Dermatol. 2018;17(7):800-803.

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