Successful use of genotypic resistance testing in HIV-1-infected individuals with detectable viraemia between 50 and 1000 copies/ml

AIDS
Laura WatersDavid Asboe

Abstract

Traditionally an HIV viral load of over 1000 copies/ml was presumed necessary for genotypic resistance testing. We performed a retrospective analysis to assess rates of viral amplification on viral loads between 50 and 1000 copies/ml. Amplification was significantly more likely for 200-1000 copies/ml than 50-200 copies/ml; most samples amplified successfully, supporting the use of genotyping for low-level viraemia.

Citations

Jun 1, 2011·The Journal of Antimicrobial Chemotherapy·Mattia C F ProsperiUNKNOWN SEHERE consortium
Aug 4, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Yumi MitsuyaRobert W Shafer
Jan 17, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maria Mercedes SantoroCarlo Federico Perno
Jan 15, 2016·Infectious Diseases·Tomas MellbergBo Svennerholm
Mar 4, 2009·Enfermedades infecciosas y microbiología clínica·Jorge Parra-RuizFederico García
Aug 25, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F Ceccherini-SilbersteinC-F Perno
Oct 15, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P-X ZhengJ-J Wu

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