PMID: 9535304Apr 16, 1998Paper

Successful use of intravenous immunoglobulins in Landau-Kleffner syndrome

Pediatric Neurology
L G LagaeP J Casaer

Abstract

A detailed history of a boy with Landau-Kleffner syndrome is presented, demonstrating a close relationship between language functioning and paroxysmal electroencephalogram activity. During a 3-year 6-month follow-up period, three abrupt deteriorations of all language functions occurred: the child became totally noninteractive with his environment within 1 week's time. Two of these deteriorations were reversed with steroid treatment, with an identical recovery phase. Intravenous immunoglobulins had a very dramatic and comparable effect in the third relapse; both language functions and electroencephalogram abnormalities were influenced significantly by the intravenous immunoglobulin treatment.

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Citations

Dec 7, 2000·Mental Retardation and Developmental Disabilities Research Reviews·K Ballaban-Gil, R Tuchman
Jul 14, 2001·Indian Journal of Pediatrics·S BharaniD J Gandhi
Dec 19, 2000·Pediatric Neurology·A W YungT N Garrison
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