Sucrose-induced ecological response of experimental dental plaques from caries-free and caries-susceptible Human volunteers.

Infection and Immunity
G E MinahJ P Finney

Abstract

Microbial succession, experimental cariogenicity, and sucrose metabolism were examined in dental plaques which developed on sterile bovine enamel inserts in acrylic palatal appliances. The appliances were worn for a period of 14 days by 10 caries-free and 10 caries-susceptible human volunteers. Three of six enamel inserts on each appliance were exposed extraorally to 10% sucrose in 0.85% saline six times a day, and three were exposed simultaneously to 0.85% saline as a control environment. The responses of the plaques to the high-sucrose environment in both caries status populations were compared. In all plaques, exposure to 10% sucrose stimulated the succession of Veillonella spp., Lactobacillus spp., Streptococcus salivarius, and, to a lesser extent, Streptococcus mutans and a decline in levels of Streptococcus sanguis, Neisseria spp., and gram-negative anaerobic rods. Plaques from caries-free mouths, in contrast to those from caries-susceptible mouths, harbored higher levels of Veillonella spp., gram-negative anaerobic rods, and Neisseria spp. and lower levels of Lactobacillus spp. Sucrose-exposed plaques from caries-free mouths also induced less enamel microhardness changes and formed less lactic acid from [14C]sucrose duri...Continue Reading

References

Jun 1, 1977·Journal of Dental Research·C A OstromJ R McGhee
Sep 1, 1977·Journal of Dental Research·R H Stevens, I D Mandel
Jan 1, 1978·Caries Research·E TheiladeJ Theilade
Jan 1, 1978·Archives of Oral Biology·W L WrobelR G Walter
Nov 1, 1979·Infection and Immunity·W J Loesche, L H Straffon
Sep 1, 1978·Infection and Immunity·W J Loesche, S A Syed
Jan 1, 1975·Caries Research·G H BowdenG L Slack
Jan 1, 1976·Caries Research·D J Purdell-LewisJ Arends
Jan 1, 1976·Caries Research·C A Ostrom, T Koulourides
Jul 1, 1975·Journal of Dental Research·L R BrownD A Johnston
Jun 1, 1975·Infection and Immunity·W J LoescheP J Loos
Oct 1, 1975·Journal of Clinical Microbiology·R P Ellen, I B Balcerzak-Raczkowski
Feb 1, 1974·Archives of Oral Biology·I L ShklairP Cullen
May 1, 1972·Journal of Dental Research·I L ShklairL G Simonson
Mar 1, 1972·Archives of Oral Biology·A N Zengo, I D Mandel
Nov 1, 1973·Archives of Oral Biology·O G GoldJ Van Houte
Dec 1, 1967·Archives of Oral Biology·H L Ritz
Oct 1, 1958·Journal of Bacteriology·M ROGOSAA J BEAMAN
Oct 1, 1951·Journal of Dental Research·M ROGOSAR F WISEMAN
Jul 1, 1965·Journal of Bacteriology·M RogosaF S Bishop
Apr 1, 1946·The American Journal of Digestive Diseases·G H CHAPMAN

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Citations

Apr 1, 1986·Scandinavian Journal of Dental Research·K WennerholmB Krasse
Jan 1, 1996·Journal of Dental Research·W H van Palenstein HeldermanF H Mikx
Jul 1, 1994·Advances in Dental Research·O FejerskovM J Larsen
Apr 1, 2000·Applied and Environmental Microbiology·J PrattenM Wilson
Apr 1, 1997·Advances in Dental Research·G H Bowden, Y H Li
Sep 26, 2006·Journal of Dental Research·A F Paes LemeJ A Cury
Mar 21, 2019·Brazilian Oral Research·Felipe Weidenbach DegraziaFabrício Mezzomo Collares
Apr 27, 2004·Pesquisa odontológica brasileira = Brazilian oral research·Livia Maria Andaló TenutaJaime Aparecido Cury
Nov 1, 1994·Journal of Dental Research·J van HouteR Kent
Oct 3, 2003·The American Journal of Clinical Nutrition·Riva Touger-Decker, Cor van Loveren
Jun 1, 1990·Infection and Immunity·B Nyvad, M Kilian

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