Sucrose sham feeding decreases accumbens norepinephrine in the rat

Physiology & Behavior
Andras Hajnal, Ralph Norgren

Abstract

Noradrenergic projections from the dorsomedial medulla reach the shell of the nucleus accumbens (NAcc), a structure implicated in both reward and feeding behavior. Despite this relationship, the effect of food reward on accumbens norepinephrine (NE) remains uninvestigated. In the course of assessing dopamine (DA) in the NAcc during sucrose ingestion [0.03, 0.1, and 0.3 M; Am. J. Physiol., Regul. Integr. Comp. Physiol., 286 (2004) R31], we also analyzed NE in the microdialysis samples from 14 ad-libitum-fed male rats. In contrast to DA, which increased with sucrose concentration (+20-47%) during sham feeding, in the same animals, NE levels were reduced (approximately -20%), regardless of sucrose concentration. These results demonstrate a novel relationship between accumbens DA and NE during orosensory stimulation with a preferred nutrient.

References

May 1, 1992·Trends in Neurosciences·G F KoobL Stinus
Dec 1, 1990·Brain Research Bulletin·L Hernandez, B G Hoebel
Oct 1, 1989·Physiology & Behavior·J D SteketeeA C Swann
May 1, 1997·Pharmacology, Biochemistry, and Behavior·R B KanarekL S Monfared
Sep 1, 1997·Pharmacology, Biochemistry, and Behavior·R B KanarekR Marks-Kaufman
Mar 18, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·J W Smith
Nov 24, 1999·Biological Psychiatry·G Aston-JonesJ Cohen

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Citations

May 10, 2011·Physiology & Behavior·Luis HernándezPedro Rada
Sep 12, 2009·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·P P SilveiraC Dalmaz
Nov 3, 2015·European Journal of Pharmacology·Jeong Won Jahng, Jong-Ho Lee
Oct 10, 2006·Brain Research Bulletin·N T Bello, A Hajnal

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