Sudden Bilateral Hearing Loss, Tinnitus, and Vertigo as Presenting Symptoms of Chronic Myeloid Leukemia

The Annals of Otology, Rhinology, and Laryngology
Nathan D CassCory D F Portnuff

Abstract

The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML). A patient case is discussed along with a review of associated literature. A patient presented with sudden onset hearing loss, tinnitus, and vertigo, and was diagnosed with CML with an initial white blood cell (WBC) count of 555 000 per microliter. The proposed etiology of otologic symptoms is hyperleukocytosis. Serial audiograms showed minimal improvement in hearing despite reduction of WBC. In cases of bilateral, sudden onset sensorineural hearing loss, evaluation for systemic causes of otologic symptoms, including CML, should be considered.

References

Jul 1, 1977·The Annals of Otology, Rhinology, and Laryngology·I Sando, T Egami
Dec 1, 1991·Journal of Clinical Pathology·N SmithE Craven
Jun 8, 1985·British Medical Journal·C K Williams, O Ogan
Sep 1, 1973·The Laryngoscope·M M PaparellaF el-Fiky
Jun 1, 1997·Leukemia & Lymphoma·C S Chim, J K Woo
Jun 3, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·M C VelingJ M Bumpous
Dec 9, 2000·Acta Haematologica·L S ResendeL Niéro-Melo
Jun 26, 2001·Clinical and Laboratory Haematology·E AndrèsP Dufour
Apr 12, 2002·The Journal of Laryngology and Otology·Sung Won ChaeSoon Jae Hwang
Apr 1, 1965·The Laryngoscope·H F SCHUKNECHTW D CHASIN
Oct 10, 2003·The New England Journal of Medicine·John M Goldman, Junia V Melo
Mar 12, 2005·Pediatric Blood & Cancer·Rahul NaithaniVarinder Singh
Jul 5, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Gül Ozbilen AcarSerap Sahin
Jan 1, 1945·Archives of Otolaryngology·J G DRUSS
Mar 1, 2012·Blood Reviews·Chezi GanzelJacob M Rowe
Mar 14, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Robert J StachlerUNKNOWN American Academy of Otolaryngology-Head and Neck Surgery

❮ Previous
Next ❯

Citations

Mar 31, 2021·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Lukas D DumbergerDouglas C Bigelow

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
leukapheresis

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Related Papers

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Gül Ozbilen AcarSerap Sahin
Postgraduate Medical Journal
S A Raza, J J Phillipps
Archives of Otolaryngology--head & Neck Surgery
D L Tucci
© 2022 Meta ULC. All rights reserved