Sudden Cardiac Death Risk Distribution in the United States Population (from NHANES, 2005 to 2012)

The American Journal of Cardiology
Kristoff A OlsonDonald M Lloyd-Jones

Abstract

Sudden cardiac death (SCD) accounts for more than half of all deaths from cardiovascular disease and is the first manifestation of heart disease in 50% of these subjects. We aimed to describe the distribution of predicted SCD risk in the general US population using a recently developed risk score. We previously developed a population-based, 10-year risk score for SCD using data from the multiracial Atherosclerosis Risk in Communities cohort, validated in the Framingham Study. We now estimate 10-year predicted SCD risk in National Health and Nutrition Examination Survey participants (pooled from cycles in 2005 to 2012) and evaluate the clinical profile of participants in lower risk (0 to 80th percentile of risk) or high risk (81st to 100th percentile of risk) strata. A total of 10,811 participants were included; the mean age of participants was 48 years, and 50% were women. The average predicted 10-year risk of SCD was 3.6% in high-risk participants (81st to 100th percentile), and 0.37% in low-risk participants (0 to 80th percentile). High-risk participants were older, had higher blood pressure, total cholesterol and body mass index, lower high-density lipoprotein, and were more likely to be men, black, smokers, and diabetic. In...Continue Reading

References

Nov 26, 2008·Progress in Cardiovascular Diseases·Sumeet S ChughJonathan Jui
Jun 6, 2015·Circulation Research·Meiso HayashiChristine M Albert
Dec 24, 2017·The American Journal of Medicine·Brittany M BogleDonald M Lloyd-Jones
Jun 14, 2018·JAMA : the Journal of the American Medical Association·UNKNOWN US Preventive Services Task ForceJohn B Wong

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Citations

Oct 10, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ricardo AvendañoYi-Hwa Liu
Apr 4, 2021·Medicina·Przemysław ŻuratyńskiPrzemysław Rutkowski

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