PMID: 9527125Apr 4, 1998Paper

Sudden deafness: lack of evidence for systemic viral infection

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
A Pitkäranta, I Julkunen

Abstract

The cause of sudden deafness remains unknown even though available evidence suggests that viral infection could be one factor involved. The presence of an interferon-inducible protein termed MxA in patients' leukocytes is a good marker of a systemic viral infection. This study included 20 patients with sudden deafness and 12 control subjects. Peripheral blood leukocytes obtained from the patients with sudden deafness did not express significantly higher levels of interferon-alpha/beta-inducible MxA protein than control subjects. In addition, no measurable interferon-alpha activity was detected in any of the serum specimens. These findings suggest that sudden deafness is not commonly associated with a systemic viral infection.

References

Jan 1, 1995·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J FähG Burg
Apr 25, 2008·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Ljiljana CvorovićStefan Hegemann

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Citations

Mar 5, 2002·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Joël Gagnebin, Raphaël Maire
Feb 1, 2008·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Saumil N MerchantJoe C Adams
Mar 11, 2011·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Dimitrios KikidisAristeidis Chrysovergis
Jan 5, 2014·Clinical Reviews in Allergy & Immunology·Oshrat E Tayer-ShifmanYuval Tal
May 31, 2011·Autoimmunity Reviews·A GrecoM De Vincentiis
Oct 21, 2015·Brazilian Journal of Otorhinolaryngology·Rauf Oğuzhan KumYonca Avci
Mar 10, 2015·American Journal of Otolaryngology·Gültekin ÖvetHabibe Övet
Nov 27, 2002·The Annals of Otology, Rhinology, and Laryngology·José Ramón García Berrocal, Rafael Ramírez-Camacho
Nov 23, 2001·Acta Oto-laryngologica·J KallinenR Grénman
Jan 2, 2001·Acta Oto-laryngologica· García Berrocal JRGJ A Vargas
Nov 30, 2010·Acta otorrinolaringológica española·Guillermo PlazaUNKNOWN Asociación Madrileña de ORL

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