Sudden elevation of liver enzymes in a 64-year-old patient: a case report.

Cases Journal
Marcus WiedmannKatharina Wölke

Abstract

Eradication of Helicobacter pylori usually consists of a 7-day course of triple therapy including metronidazole or amoxicillin plus clarithromycin plus a proton pump inhibitor. We report about a rare adverse event of Hp eradication in a patient with moderate chronic and moderate active pangastritis. Shortly after the end of treatment cholestatic hepatitis occurred which was most likely related to clarithromycin, perhaps enhanced by amoxicillin. Since liver dysfunction was self-limited, no further treatment was required. In summary, clinicians should be aware about the presented rare adverse event of Helicobacter pylori eradication treatment for a close monitoring of those patients and rapid management of acute liver failure.

References

Apr 1, 1983·Anesthesiology·L StruninJ M Davies
Aug 1, 1995·International Journal of Dermatology·S Gallardo-QuesadaC Guanyabens-Calvet
Apr 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·B A BrownW Girard
Jun 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W W YewC W Leung
May 1, 1993·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·D R GuayJ C Craft
Jul 1, 1995·British Journal of Clinical Pharmacology·L A García-RodríguezG Simon
Sep 1, 1996·Journal of Clinical Gastroenterology·J Pedro-BotetM Bruguera
Jun 5, 2002·Journal of Clinical Pharmacology·Jean C FoxRobert A Levine
Dec 31, 2002·The Annals of Pharmacotherapy·Andreas TietzStephan Krähenbühl
Sep 28, 2005·Digestive Diseases and Sciences·Robert J FontanaWilliam M Lee
May 25, 2006·The Annals of Pharmacotherapy·Antonietta GiannattasioRaffaele Iorio
Jan 22, 2009·Zeitschrift für Gastroenterologie·W FischbachM Vieth

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies
biopsy

Related Concepts

Related Feeds

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Journal of the European Academy of Dermatology and Venereology : JEADV
E RallisL Saltos
British Journal of Clinical Pharmacology
Johanna StrandellI Ralph Edwards
International Journal of Clinical Pharmacology and Therapeutics
T Fidan, V Fidan
© 2022 Meta ULC. All rights reserved