PMID: 16520850Mar 8, 2006Paper

Sudden unexpected cardiac death as a function of time since the detection of electrocardiographic and clinical risk factors in apparently healthy men: the Manitoba Follow-Up Study, 1948 to 2004

The Canadian Journal of Cardiology
T Edward Cuddy, Robert B Tate

Abstract

As the first and only manifestation of ischemic heart disease, sudden unexpected cardiac death (SUCD) is a serious clinical and epidemiological concern. Prospective population studies permit the identification of risk factors for SUCD. Knowledge of the short-and long-term risks for SUCD are key to understanding the basis of any intervention. The present paper explores the effect of time since the detection of factors on the risk for SUCD. The Manitoba Follow-Up Study is a longitudinal, prospective study of 3983 originally healthy young men who have been followed with routine medical examinations since 1948. During 56 years of follow-up, SUCD occurred in 171 men. This analysis examined 21 possible risk factors for SUCD, including clinical findings, social variables and electrocardiographic abnormalities. Time-dependent covariate Cox proportional hazard models were used to estimate age-adjusted relative risks for SUCD. In multivariate models, the relative risk of SUCD was estimated as a function of time since the documentation of each risk factor. Excess alcohol consumption and T wave changes were associated with a high short-term risk for SUCD. Arterial hypertension and ST/T changes had sustained excess risk over both the short ...Continue Reading

References

May 27, 1978·British Medical Journal·W G HughsonI Walton
Nov 1, 1992·British Heart Journal·G Wannamethee, A G Shaper
Jun 1, 1987·American Heart Journal·W B KannelL A Cupples
Jun 1, 1985·Journal of the American College of Cardiology·W B Kannel, A Schatzkin
Apr 1, 1971·The American Journal of Cardiology·W B KannelM J Schwartz
Aug 1, 1995·American Heart Journal·J DuflouJ Smialek
Apr 1, 1996·Journal of the American College of Cardiology·H V Barron, M D Lesh
Feb 19, 1997·JAMA : the Journal of the American Medical Association·M G HuninkM C Weinstein
Aug 1, 1997·Heart·G PochmalickiH Jibril
Mar 11, 2000·Obesity Research·A P LalaniL E Shapiro
Jan 10, 2003·The New England Journal of Medicine·Kenneth J MukamalEric B Rimm
May 3, 2003·American Journal of Preventive Medicine·Mary V DavisWilliam W Greaves
Oct 23, 2003·The Gerontologist·Robert B TateT Edward Cuddy

❮ Previous
Next ❯

Citations

Jan 11, 2007·Herzschrittmachertherapie & Elektrophysiologie·A Brandt, D C Gulba
Sep 24, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jose Jayme Galvão De LimaEduardo M Krieger
Jul 13, 2012·BMC Medical Research Methodology·Amalia KarahaliosJulie A Simpson
Jul 6, 2014·Heart & Lung : the Journal of Critical Care·Salah S Al-ZaitiMary G Carey
Sep 24, 2015·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Jani T TikkanenM Juhani Junttila
Jul 30, 2014·International Journal of Epidemiology·Robert B TateFrancis A L Mathewson
Sep 10, 2013·The American Journal of Cardiology·Philippe MauryVincent Probst
Apr 23, 2016·PloS One·Young Sun RoUNKNOWN Cardiac Arrest Pursuit Trial with Unique Registry and Epidemiologic Surveillance (CAPTURES) investigators
Jun 21, 2007·International Journal of Technology Assessment in Health Care·Jacob A UdellMuhammad M Mamdani
Mar 3, 2007·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Timothy W Smith, Michael E Cain
Apr 15, 2010·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·J R TimmerF Zijlstra
Aug 7, 2009·Experimental Biology and Medicine·Mark R HolcombVeniamin Y Sidorov
May 11, 2012·Journal of Hypertension·Tetsuya OhiraHiroyasu Iso
Feb 8, 2018·Terapevticheskiĭ arkhiv·L A BockeriaE E Achkasov
May 21, 2019·International Heart Journal·Hui ChenShunhui Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.