Suffocation of nerve fibers by living nanovesicles: a model simulation

Journal of Proteome Research
Andrei P Sommer

Abstract

A model using nanospheres to allow the simulation of the nonspecific interaction of nanobacteria (NB), one with another or with body tissues, is established. Depending primarily on their concentrations and stress levels, these apatite nanovesicles may nucleate thrombogenic conglomerates in blood, or self-assemble to dense nanoclay layers on surfaces in the body. Partial or total encapsulation of nerve fiber bundles by such mineral layers may interrupt the metabolic exchanges between the surrounded tissue and its immediate environment and may restrict signaling processes. The presented model could provide detailed insight into plaque formation triggered by NB, and the parameters encouraging it.

References

Mar 1, 1988·Neuropathology and Applied Neurobiology·R H KingP J Watkins
May 1, 1981·Muscle & Nerve·H KalimoM Haltia
Jul 8, 1998·Proceedings of the National Academy of Sciences of the United States of America·E O Kajander, N Ciftçioglu
Dec 10, 2002·Journal of Clinical Laser Medicine & Surgery·Andrei P SommerE Olavi Kajander
Mar 21, 2003·Journal of Proteome Research·Andrei P SommerAdam R Mester
Sep 19, 2003·Journal of Clinical Laser Medicine & Surgery·Andrei P SommerHarry T Whelan
Oct 10, 2003·Advances in Cardiology·Edward C Klatt

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Citations

Nov 24, 2004·International Journal of Antimicrobial Agents·Andrei P Sommer, N Chandra Wickramasinghe
Jun 15, 2005·Journal of Proteome Research·Andrei P Sommer
Dec 15, 2004·Journal of Proteome Research·Andrei P SommerShirwan Al-Mufti

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