Sugar-based novel chiral macrocycles for inclusion applications and chiral recognition

Carbohydrate Research
Ankita SinghAshok K Prasad

Abstract

A convergent template assisted synthesis of sugar-based chiral macrocycles has been achieved. The host-guest inclusion studies have revealed significant interactions of the synthesized macrocycle with primary over secondary ammonium salt. The chiral macrocyle also discriminates between D- and L-phenylalanine methyl ester hydrochlorides as revealed by (1)H NMR spectral studies on the mixture of the host and the guest molecules.

References

Oct 2, 2002·Chemistry : a European Journal·Sibylle A W GrunerHorst Kessler
Aug 5, 2003·The Journal of Organic Chemistry·T K ChakrabortyA C Kunwar
Dec 18, 2003·Drug Discovery Today·Hartmuth C Kolb, K Barry Sharpless
Sep 24, 2005·Organic Letters·Kyle D BodineMary S Gin
Apr 15, 2008·Journal of the American Chemical Society·Chunsheng ZhuBiao Yu
Jul 2, 2008·Nature Reviews. Drug Discovery·Edward M DriggersNicholas K Terrett
Dec 3, 2008·Chemical Communications : Chem Comm·Bartosz Lewandowski, Slawomir Jarosz
Jan 13, 2010·Dalton Transactions : an International Journal of Inorganic Chemistry·Harriet StruthersRoger Schibli
May 6, 2010·Organic Letters·Bartosz Lewandowski, Slawomir Jarosz
Jul 30, 2010·The Journal of Organic Chemistry·Lin XieJin-Song Yang
Nov 26, 2010·Chemical Communications : Chem Comm·Mauro Lo ConteAlberto Marra
Sep 29, 2011·Chemistry, an Asian Journal·Sandip G AgalaveVandana S Pore
Jun 1, 2012·The Journal of Organic Chemistry·Nirmal Das Adhikary, Partha Chattopadhyay
Mar 2, 2013·Angewandte Chemie·Seiji Shirakawa, Keiji Maruoka
May 28, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xufen Yu, Dianqing Sun
Jul 10, 2014·Chemical Reviews·Juan Xie, Nicolas Bogliotti
Feb 7, 2015·Carbohydrate Research·Abbas Abdulameer SalmanRusnah Syahila Duali Hussen

❮ Previous
Next ❯

Citations

Dec 17, 2016·Carbohydrate Research·Michał Kowalski, Sławomir Jarosz
Mar 5, 2019·Current Medicinal Chemistry·Kartikey Singh, Rama Pati Tripathi
Aug 22, 2017·Analytical Methods : Advancing Methods and Applications·Gabe NagyNicola L B Pohl
Jun 25, 2021·Chemical Reviews·Anand K AgrahariVinod K Tiwari
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Surya B AdhikariGuijun Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.