Suggestion of response evaluation criteria in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma (OAML)

Annals of Hematology
Su Kyung JungSeok-Goo Cho

Abstract

Ocular adnexal mucosa-associated lymphoid tissue lymphoma (OAML) has been recognized as most common primary orbital malignancy. However, little was known about the response criteria for OAML. Our aim was to suggest response criteria for nonconjunctival OAML; the response evaluation of which using the conventional response criteria is inappropriate. A retrospective chart review of 34 eyes from 30 patients diagnosed with nonconjunctival OAML was conducted, focusing on the change in tumor size based on linear bi-dimensional and three-dimensional methods in magnetic resonance imaging (MRI) of the orbit. The maximum tumor response period of each case was investigated, and the expected optimal response period was calculated using regression analysis. In 30 evaluable patients, the median time taken for the maximum tumor response was 6 months (range, 3-18). More than 75 % of patients attained maximal tumor response in 6 months after initial therapy for follow-up period, the median value of which was 30 months (range, 15-77). Based on the regression analysis, it took 4.7 months for the maximum diameter (2r) of tumor to decrease by 50 % of initial lesion size. We cautiously suggest that optimal response could be defined as 50 % reduction...Continue Reading

References

Mar 24, 1999·Journal of the National Cancer Institute·K JamesP Therasse
Sep 7, 2002·Archives of Ophthalmology·Bita EsmaeliRobert A Newman
Feb 28, 2003·International Journal of Radiation Oncology, Biology, Physics·Sylvie MartinetRené Olivier Mirimanoff
Aug 12, 2003·International Journal of Radiation Oncology, Biology, Physics·Masatoshi HasegawaTakashi Nakano
Nov 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Richard W TsangBruce J Patterson
Dec 20, 2003·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sarah E CouplandHarald Stein
May 4, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Markus RadererAndreas Chott
Oct 21, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K TanimotoK Tobinai
Mar 2, 2006·Journal of the National Comprehensive Cancer Network : JNCCN·Andrew D ZelenetzUNKNOWN National Comprehensive Cancer Network
Apr 28, 2006·Blood·Didier DecaudinLivia Lumbroso-Le Rouic
Jan 24, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bruce D ChesonUNKNOWN International Harmonization Project on Lymphoma
Aug 7, 2007·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Isis GayedBita Esmaeli
Apr 15, 2008·American Journal of Ophthalmology·Frederick A Jakobiec
Jul 18, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andrés J M FerreriRiccardo Dolcetti

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Citations

Nov 23, 2019·EJNMMI Research·Hye Lim ParkUNKNOWN Catholic University Lymphoma Group

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