Suicidal ideation, hopelessness, and affective temperament in patients with blepharospasm.

International Journal of Psychiatry in Clinical Practice
Isabella BerardelliMaurizio Pompili

Abstract

The aim of this study was to investigate the relationship between suicidal ideation and neurological, psychological, and psychiatric features in patients with blepharospasm (BSP). We enrolled 70 BSP patients and 80 control subjects. All participants underwent a psychiatric and psychometric evaluation: Structured Clinical Interview, Clinical Global Impression, Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, Columbia-Suicide Severity Rating Scale, Beck Hopelessness Scale, Temperament Evaluation of Memphis, Pisa, San Diego Auto-questionnaire. BSP severity was assessed using the Blepharospasm Severity Rating Scale. Suicidal ideation was reported in 18% of BSP patients and 6% had current suicidal ideation. 83% of BSP patients had severe hopelessness. BSP patients presented an increased sense of hopelessness (OR= 1.39, 95% CI = 1.13/1.70) and a pronounced depressive temperament (OR= 1.36, 95% CI = 1.12/1.65). Suicidal ideation in BSP patients correlated with psychiatric disorders (OR = 3.96, 95% CI = 1.23/12.74) and higher scores on the HAM-A (OR = 1.11, 95% CI = 1.02/1.20), HAM-D (OR = 1.18, 95% CI = 1.05/1.32), CGI (OR = 1.85, 95% CI = 1.18/2.90), TEMPS-A Cyclothymia (OR = 1.16, 95% CI = 1.02/1.31). Our findings su...Continue Reading

Associated Clinical Trials

References

Jun 15, 2007·Psychological Reports·Maurizio PompiliDavid Lester
Jan 29, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Giovanni FabbriniAlfredo Berardelli
Jan 12, 2012·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Massimo PasquiniMassimo Biondi
Oct 31, 2012·Clinical Neurology and Neurosurgery·Marco InnamoratiPaolo Martelletti
Jun 19, 2013·Neurology·Giovanni DefazioAlfredo Berardelli
Jul 31, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·H A JinnahUNKNOWN Dystonia Coalition Investigators
May 27, 2014·Journal of Affective Disorders·Serap Erdoğan Taycan, Okan Taycan
Apr 8, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Giovanni DefazioAlfredo Berardelli
Aug 5, 2015·Psychiatry Research·Isabella BerardelliGiovanni Fabbrini
Sep 12, 2015·Parkinsonism & Related Disorders·Antonella ConteGiovanni Fabbrini
Dec 20, 2016·Journal of Affective Disorders·Ross J BaldessariniMaurizio Pompili
Jan 1, 2017·International Journal of Cardiology·Bahareh EslamiJamie L Jackson
Feb 12, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Giovanni DefazioAlfredo Berardelli
Apr 1, 2017·Nöro Psikiyatri Arşivi·Adile ÖzkanHandan Işın Özişik Karaman
Jan 6, 2018·Harvard Review of Psychiatry·Gustavo H VázquezRoss J Baldessarini
Oct 20, 2018·International Journal of Clinical Practice·Isabella BerardelliMaurizio Pompili
Dec 7, 2018·Expert Review of Neurotherapeutics·Isabella BerardelliGiovanni Fabbrini
Mar 11, 2019·Parkinsonism & Related Disorders·Daniele BelvisiMaurizio Pompili

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Citations

Jul 17, 2021·International Journal of Psychiatry in Clinical Practice·Isabella BerardelliGiovanni Fabbrini
Aug 8, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Alex Medina EscobarZahra Goodarzi

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