Suicidal Zinc Phosphide Poisoning Unmasking Brugada Syndrome and Triggering Near Fatal Ventricular Arrhythmia

Pacing and Clinical Electrophysiology : PACE
Mukund A PrabhuJayaprakash Shenthar

Abstract

Brugada syndrome (BrS) is an inherited channelopathy associated with increased incidence of ventricular arrhythmias and has many acquired triggers. Zinc phosphide (ZnP) is a rodenticide and is commonly implicated in suicidal poison ingestion. ZnP poisoning can cause myocardial toxicity and death. We report a case of ZnP poisoning that triggered a type I Brugada pattern and ventricular fibrillation in a 67-year-old male. He had no other features of toxicity and recovered later. As metal phosphide is the commonest toxin involved in suicidal poisoning in India and BrS being endemic here, this case highlights an important clinical problem.

References

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Citations

Nov 1, 2015·Pacing and Clinical Electrophysiology : PACE·Mukund A PrabhuJayaprakash Shenthar
Nov 1, 2015·Pacing and Clinical Electrophysiology : PACE·Byron H GottschalkAdrian Baranchuk
Aug 16, 2016·Clinical Case Reports·Zohreh OghabianHamid Reza Rahimi
Jan 10, 2018·Medicinal Research Reviews·Přemysl MladěnkaUNKNOWN TOX-OER and CARDIOTOX Hradec Králové Researchers and Collaborators
May 27, 2020·Cardiovascular Toxicology·Parinaz ParhizgarHossein Hassanian-Moghaddam

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