Suicidality among psoriasis patients: a critical evidence synthesis

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia
Kevin K Wu, April W Armstrong

Abstract

Psoriasis is a chronic inflammatory skin disease with under-investigated and underappreciated links to psychiatric comorbidities, including anxiety, depression, and suicidality. In this review, we synthesize and discuss the literature investigating the association between psoriasis and three measures of suicidality: suicidal ideation, suicide attempts, and completed suicide. Studies have shown that psoriasis is significantly linked to all three measures of suicidality, but the available data on suicide attempts and completed suicides is limited and less consistent. Studied risk factors for suicidality in psoriasis patients include age, gender, and severity of psoriasis. Younger patients and patients with more severe psoriasis are at significantly higher risk of suicidality; gender was not associated with suicidality in most studies. Higher levels of psoriasis-related stressors and decrements to quality of life were significantly associated with suicidality in psoriasis patients. Most biologic treatments for psoriasis appear to be helpful in decreasing rates of depression, but data on their impact on suicidality is less well known. Understanding the risk of suicidality in psoriasis patients is key to engaging all stakeholders to...Continue Reading

References

Jan 1, 1989·Journal of the American Academy of Dermatology·I H Ginsburg, B G Link
Jan 1, 1987·Clinical and Experimental Dermatology·A Y Finlay, S E Kelly
Jun 1, 1994·The Journal of Investigative Dermatology·J T ElderJ J Voorhees
Mar 1, 1993·International Journal of Dermatology·M A GuptaC N Ellis
Jan 1, 1993·Dermatology : International Journal for Clinical and Investigative Dermatology·A E SmithW E Beer
Jul 23, 1998·Journal of the American Academy of Dermatology·E J Primka, C Camisa
Sep 19, 2001·The Journal of Dermatology·N SharmaR K Singh
Oct 30, 2003·Medical Care·Kurt KroenkeJanet B W Williams
Apr 16, 2004·The Journal of Investigative Dermatology. Symposium Proceedings·Robert S SternTara Rolstad
Jun 19, 2004·Acta Dermato-venereologica·Robert ZachariaeHans Christian Wulf
Jan 13, 2006·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Tal FriedmanYoram Barak
Feb 21, 2006·Journal of the American Academy of Dermatology·Angelo PicardiPaolo Pasquini
Aug 3, 2007·The Journal of Dermatological Treatment·Lena RingJörgen Serup
Jan 28, 2010·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Karlijn J JolingHarm W J van Marwijk
Apr 27, 2010·Dermatologic Therapy·Jennifer Hayes, John Koo
Jul 17, 2010·The British Journal of Dermatology·K AbuabaraJ M Gelfand
Apr 20, 2011·Journal of Injury & Violence Research·Ajit Shah
May 24, 2011·Journal of Dermatological Science·April W ArmstrongJohn C Rutledge
Oct 1, 1997·Journal of Health Psychology·S R RappA Clark
Jun 19, 2012·Cellular & Molecular Immunology·Yihua CaiJun Yan
Sep 28, 2012·The Journal of Investigative Dermatology·Rosa ParisiUNKNOWN Identification and Management of Psoriasis and Associated ComorbidiTy (IMPACT) project team
Jan 31, 2013·Journal of the American Academy of Dermatology·April W ArmstrongEhrin J Armstrong
Feb 15, 2013·JAMA Dermatology·April W ArmstrongEhrin J Armstrong
Nov 26, 2013·Journal of Affective Disorders·Livia SannaLana J Williams
Jan 7, 2014·Journal of the American Academy of Dermatology·Tara D RachakondaApril W Armstrong
Jun 26, 2015·Physiological Reviews·Lionel A TintignacMarkus A Rüegg
Aug 15, 2015·Journal of Cutaneous Medicine and Surgery·Patrick FlemingCharles Lynde
Oct 18, 2015·The Medical Clinics of North America·Kathryn T Shahwan, Alexa B Kimball
Dec 26, 2015·Journal of the American Academy of Dermatology·Melissa J Danesh, Alexa B Kimball
May 22, 2016·Journal of Cutaneous Medicine and Surgery·Melinda GooderhamKim Papp
Sep 14, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·P FlemingW P Gulliver
Sep 30, 2016·The Journal of International Medical Research·Maurizio PompiliAntonio Costanzo
Mar 23, 2017·International Journal of Psychiatry in Clinical Practice·Maurizio PompiliPaolo Girardi
Jul 7, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·J KooJ J Wu
Aug 16, 2017·Journal of the American Academy of Dermatology·Sanminder SinghApril W Armstrong
Sep 12, 2017·Psychosomatics·Deepak PrabhakarBrian K Ahmedani
Oct 24, 2017·The Journal of Dermatological Treatment·J J WuL B Marangell
Dec 12, 2017·The Journal of Dermatology·Masahiro Kamata, Yayoi Tada

❮ Previous
Next ❯

Citations

Jan 17, 2021·Journal of Psychosomatic Research·Maurizio PompiliRoss J Baldessarini

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Skin Therapy Letter
Mathew N Nicholas, Melinda J Gooderham
Journal of Cutaneous Medicine and Surgery
Mathew N Nicholas, Melinda J Gooderham
Journal of the American Academy of Child and Adolescent Psychiatry
Anat Brunstein KlomekMadelyn S Gould
© 2022 Meta ULC. All rights reserved