PMID: 7036765Jan 1, 1982Paper

Sulfadoxine-pyrimethamine for the treatment of acute malaria in children of Papua New Guinea. II. Plasmodium vivax

The American Journal of Tropical Medicine and Hygiene
B DarlowM P Alpers

Abstract

In Papua New Guinea, Plasmodium falciparum and P. vivax are common causes of acute malaria in children and P. malariae an uncommon cause. The increasing prevelance of chloroquine-resistant strains of P. falciparum in Papua New Guinea has prompted the search for alternatives to chloroquine as standard presumptive treatment. Sulfadoxine-pyrimethamine, either alone or in combination with a single dose of chloroquine, was compared with chloroquine alone for treatment of acute vivax malaria in children in Madang. Fever resolution was slowest in the group treated with sulfadoxine-pyrimethamine alone, and time to clearance of parasitemia was significantly longer in this group (P less than 0.001). Where possible, species identification should be undertaken in acute malaria and cases of P. vivax treated with chloroquine.

Citations

Jul 15, 1982·The New England Journal of Medicine·I K Schwartz, C C Campbell
Mar 4, 2006·Transactions of the Royal Society of Tropical Medicine and Hygiene·Neena ValechaPascal Ringwald
Oct 12, 2011·Current Opinion in Infectious Diseases·Ric N PriceLorenz von Seidlein
Dec 30, 2011·PLoS Neglected Tropical Diseases·Cristian KoepfliIngrid Felger
Jul 1, 1988·Antimicrobial Agents and Chemotherapy·D J KrogstadP H Schlesinger
Sep 27, 2005·Molecular and Biochemical Parasitology·Sonia Y HuntCarol Hopkins Sibley

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.