Sulfadoxine/pyrimethamine or chloroquine/clindamycin treatment of Gabonese school children infected with chloroquine resistant malaria

The Journal of Antimicrobial Chemotherapy
W MetzgerP G Kremsner

Abstract

In a randomized trial, a high dosage chloroquine monotherapy (45 mg/kg over 3 days) was compared with combination regimens of sulfadoxine/pyrimethamine and chloroquine/clindamycin for treating Gabonese school children with Plasmodium falciparum malaria. In chloroquine treated patients only 32% were ultimately cured. In contrast, more than 90% of patients were cured after treatment with either combination regimen.

Citations

Nov 1, 1995·Transactions of the Royal Society of Tropical Medicine and Hygiene·W G MetzgerP G Kremsner
Jul 18, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·P DeloronN Elissa
Aug 15, 2002·Transactions of the Royal Society of Tropical Medicine and Hygiene·Poul-Erik KofoedLars Rombo
Mar 11, 2003·Transactions of the Royal Society of Tropical Medicine and Hygiene·S BorrmannP G Kremsner
Feb 17, 1998·Transactions of the Royal Society of Tropical Medicine and Hygiene·R Schmidt-OttP G Kremsner
May 1, 1997·Parasitology Today·P G KremsnerW Graninger
Mar 21, 2012·Antimicrobial Agents and Chemotherapy·Christian SupanBertrand Lell
Jul 18, 2002·Antimicrobial Agents and Chemotherapy·Bertrand Lell, Peter G Kremsner
Apr 14, 2010·Wiener klinische Wochenschrift·Benjamin Mordmüller
Jan 31, 2012·Cellular and Molecular Life Sciences : CMLS·Robert L SummersRowena E Martin
Nov 12, 2015·Malaria Journal·Tiphaine GaillardBruno Pradines

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