Sulfation made simple: a strategy for synthesising sulfated molecules

Chemical Communications : Chem Comm
Daniel M GillAlan M Jones


The study of organosulfates is a burgeoning area in biology, yet there are significant challenges with their synthesis. We report the development of a tributylsulfoammonium betaine as a high yielding route to organosulfates. The optimised reaction conditions were interrogated with a diverse range of alcohols, including natural products and amino acids.


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Methods Mentioned

ion-exchange chromatography

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