SULFATION PATHWAYS: Insights into steroid sulfation and desulfation pathways

Journal of Molecular Endocrinology
Paul A Foster, Jonathan Wolf Mueller

Abstract

Sulfation and desulfation pathways represent highly dynamic ways of shuttling, repressing and re-activating steroid hormones, thus controlling their immense biological potency at the very heart of endocrinology. This theme currently experiences growing research interest from various sides, including, but not limited to, novel insights about phospho-adenosine-5'-phosphosulfate synthase and sulfotransferase function and regulation, novel analytics for steroid conjugate detection and quantification. Within this review, we will also define how sulfation pathways are ripe for drug development strategies, which have translational potential to treat a number of conditions, including chronic inflammatory diseases and steroid-dependent cancers.

References

Sep 1, 1990·The Journal of Steroid Biochemistry and Molecular Biology·R C Tuckey
Jan 1, 1987·Reproduction, Nutrition, Development·L CancelaL Miravet
Jan 1, 1994·Gynecologic and Obstetric Investigation·I MiyakawaN Mori
Aug 12, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·K von FiguraT Dierks
Apr 3, 2001·The Journal of Steroid Biochemistry and Molecular Biology·S P NewmanM J Reed
Jun 12, 2002·Biochemical and Biophysical Research Communications·Sandra GoettschPeter Bayer
Oct 9, 2002·Proceedings of the National Academy of Sciences of the United States of America·Junichiro SonodaRonald M Evans
Mar 21, 2003·Pediatric Neurosurgery·Andrew JeaGlenn Morrison
Mar 27, 2003·The Journal of Biological Chemistry·Francisco G Hernandez-GuzmanDebashis Ghosh
May 1, 1962·The Journal of Clinical Investigation·J R PASQUALINI, M F JAYLE
Feb 24, 2004·Molecular Pharmacology·Ibtissam EchchgaddaBandana Chatterjee
Jun 17, 2004·American Journal of Physiology. Endocrinology and Metabolism·Min Sun KimKenneth R Feingold
Nov 24, 2004·Drug Metabolism Reviews·Frederick C Kauffman
Nov 25, 2004·Endocrine Reviews·M J ReedB V L Potter
Mar 10, 2005·The Journal of Clinical Endocrinology and Metabolism·Fabian HammerWiebke Arlt
Jul 25, 2006·Journal of Molecular Biology·Sandra GoettschCristina Hartmann-Fatu
Jan 9, 2008·Molecular and Cellular Endocrinology·Chloe StengelAtul Purohit
Oct 18, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Paul A FosterAtul Purohit
Oct 22, 2008·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·K J BrookesL Kent
Mar 3, 2009·Biological Psychiatry·William DaviesLawrence S Wilkinson
May 29, 2009·The New England Journal of Medicine·Cees NoordamWiebke Arlt
Jan 19, 2010·Journal of the American Academy of Dermatology·Neil F FernandesRobert A Schwartz
Mar 2, 2010·The Journal of Steroid Biochemistry and Molecular Biology·Cedric Shackleton
Apr 13, 2010·Biochemical and Biophysical Research Communications·Daniel GrumJonathan W Mueller
Jun 1, 2010·Endocrinology and Metabolism Clinics of North America·Bruce W Hollis
Jun 29, 2010·The Journal of Steroid Biochemistry and Molecular Biology·Martin HillLuboslav Stárka
Feb 2, 2011·BMC Biotechnology·Morten E MøldrupBarbara A Halkier
Mar 28, 2012·The Journal of Biological Chemistry·Johannes van den BoomJonathan W Mueller
Jan 8, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Mark P Thomas, Barry V L Potter
Jan 16, 2013·International Journal of Colorectal Disease·Paul A Foster
Apr 13, 2013·Molecular Endocrinology·Young-Kyo SeoBandana Chatterjee

❮ Previous
Next ❯

Citations

Aug 15, 2018·The Journal of Experimental Biology·Z Yan Wang, Clifton W Ragsdale
Mar 19, 2019·Chemical Communications : Chem Comm·Daniel M GillAlan M Jones
Jul 23, 2019·Cell Biochemistry and Function·Carl Jenkinson
Jul 25, 2019·International Journal of Molecular Sciences·Donatella PastoreDavid Della-Morte
May 28, 2019·Frontiers in Molecular Biosciences·Oliver BrylskiJonathan W Mueller
Jul 5, 2019·The Journal of Biological Chemistry·Süleyman GünalJonathan Wolf Mueller
Jan 17, 2021·Molecular and Cellular Endocrinology·Thomas Alec LightningJonathan Wolf Mueller
Mar 8, 2021·Molecular and Cellular Endocrinology·Typhanie Dumontet, Antoine Martinez
May 1, 2021·Biomedicines·Nina Horn, Pernilla Wittung-Stafshede
Mar 20, 2021·The Journal of Clinical Endocrinology and Metabolism·Jonathan Wolf MuellerMatthias Kroiss
Dec 2, 2020·Current Drug Metabolism·Sangita M DuttaSmarajit Maiti
Sep 28, 2021·The Journal of Clinical Endocrinology and Metabolism·Carl JenkinsonDavid J Handelsman
Dec 5, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Heidi N du PreezJohnson Lin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical & Translational Endocrinology
Vin Tangpricha
Casopís lékar̆ů c̆eských
Z Matys, K Horký
Duodecim; lääketieteellinen aikakauskirja
R VihkoO A Jänne
Annual Review of Medicine
C DODDSS A SIMPSON
© 2022 Meta ULC. All rights reserved