Sulfonated Polyaniline as Zwitterionic and Conductive Interfaces for Anti-Biofouling on Open Electrode Surfaces in Electrodynamic Systems.

ACS Applied Materials & Interfaces
Chun-Wei LeeFan-Gang Tseng

Abstract

Electrodynamic systems for bioanalytical applications constantly suffer from biofouling due to electrical field-induced nonspecific bioadsorption on electrode surfaces. To minimize this issue, surface modification using anti-biofouling and conductive materials is necessary to not only protect the electrode surface from nonspecific bioadsorption but also maintain desired electrodynamic properties for electrode operation. In this study, we designed and prepared a conductive, zwitterionic, and self-doped sulfonated polyaniline (SPANI) coating on Au electrode surfaces for anti-biofouling applications. The zwitterionic coating was fabricated by electrochemical polymerization of aniline on the Au electrode surface functionalized with cysteamine (HS-CH2CH2-NH2) and then a post-polymerization treatment with fuming sulfuric acid. We found that the SPANI-coated electrodes exhibited an excellent anti-biofouling ability in dielectrophoresis (DEP) capturing-and-releasing processes, with a very low average residual mass rate of 1.44% for the SPANI-5s electrode, whereas electrodes modified with poly(ethylene glycol) (PEG) gave an average residual mass rate of 14.30%. Even under continuous operation for more than 1 h, the SPANI-5s electrode st...Continue Reading

References

May 15, 1985·The Biochemical Journal·C M Mendel, D B Mendel
Jun 7, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Mi Ran ParkChong Su Cho
Jun 15, 2006·The Journal of Physical Chemistry. B·Zheng ZhangShaoyi Jiang
May 15, 2007·Colloids and Surfaces. B, Biointerfaces·Pen-Cheng WangJoel S Bennett
Sep 30, 2008·Biomaterials·Guozhu LiShaoyi Jiang
Oct 1, 2009·Lab on a Chip·Aldrich N K LauMing C Wu
Dec 18, 2013·Electrophoresis·Talukder Z JuberyPrashanta Dutta
May 12, 2015·Journal of medical and biological engineering·Hongbin Zhang, Mu Chiao
Dec 28, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Clayton S CampeloDiego Mantovani
Mar 9, 2018·Journal of the Royal Society, Interface·Jimin FuHaimin Yao
Apr 17, 2018·ACS Applied Materials & Interfaces·Sefika OzcanAyse Asatekin
Jul 16, 2001·Angewandte Chemie·Alan G MacDiarmid
Jul 14, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Tatsuro Goda, Yuji Miyahara

❮ Previous
Next ❯

Citations

Feb 19, 2021·Biosensors & Bioelectronics·Shuang ZhaoGuixue Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.