Sulphate in pregnancy

Nutrients
Paul A DawsonFrancis G Bowling

Abstract

Sulphate is an obligate nutrient for healthy growth and development. Sulphate conjugation (sulphonation) of proteoglycans maintains the structure and function of tissues. Sulphonation also regulates the bioactivity of steroids, thyroid hormone, bile acids, catecholamines and cholecystokinin, and detoxifies certain xenobiotics and pharmacological drugs. In adults and children, sulphate is obtained from the diet and from the intracellular metabolism of sulphur-containing amino acids. Dietary sulphate intake can vary greatly and is dependent on the type of food consumed and source of drinking water. Once ingested, sulphate is absorbed into circulation where its level is maintained at approximately 300 μmol/L, making sulphate the fourth most abundant anion in plasma. In pregnant women, circulating sulphate concentrations increase by twofold with levels peaking in late gestation. This increased sulphataemia, which is mediated by up-regulation of sulphate reabsorption in the maternal kidneys, provides a reservoir of sulphate to meet the gestational needs of the developing foetus. The foetus has negligible capacity to generate sulphate and thereby, is completely reliant on sulphate supply from the maternal circulation. Maternal hyposu...Continue Reading

References

Sep 1, 1979·Journal of Animal Science·D W PatersonO E Olson
Jan 1, 1990·American Journal of Nephrology·J RicciC A Vaamonde
Nov 1, 1989·Toxicology and Applied Pharmacology·V F Price, D J Jollow
Mar 1, 1989·Archives of Environmental Health·H E AllenC N Hass
Jan 1, 1987·Journal of Toxicology. Clinical Toxicology·M E MorrisS C Sutton
Mar 1, 1986·Medical Toxicology·A T ProudfootE H Dyson
Apr 1, 1982·Archives of Biochemistry and Biophysics·K Sugahara, N B Schwartz
Jan 1, 1983·Annals of Nutrition & Metabolism·J T Smith, R V Acuff
Mar 1, 1984·American Journal of Obstetrics and Gynecology·D E ColeL J Stirk
Jan 1, 1980·Advances in Clinical Chemistry·T Lind
Mar 1, 1981·Journal of Pharmaceutical Sciences·D M Cocchetto, G Levy
Dec 1, 1996·Endocrine Reviews·C A Strott
May 1, 1997·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·C D Klaassen, J W Boles
Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·K KurimaN B Schwartz
Jul 20, 1999·Molecular and Cellular Endocrinology·V M DarrasT J Visser
Sep 13, 2000·Critical Reviews in Clinical Laboratory Sciences·D E Cole, J Evrovski
Jan 24, 2002·The Journal of Pharmacology and Experimental Therapeutics·Ronald N Hines, D Gail McCarver
Jan 24, 2002·The Journal of Pharmacology and Experimental Therapeutics·D Gail McCarver, Ronald N Hines
Oct 10, 2002·Endocrine Reviews·Charles A Strott
Oct 28, 2003·Proceedings of the National Academy of Sciences of the United States of America·Paul A DawsonDaniel Markovich
Jun 25, 2004·Proceedings of the National Academy of Sciences of the United States of America·Holger ThieleStefan Mundlos
Aug 18, 2004·Behavioural Brain Research·Paul Anthony DawsonDaniel Markovich
Oct 7, 2004·Glycoconjugate Journal·Hiroko HabuchiKoji Kimata
Feb 22, 2005·Current Medicinal Chemistry·P A Dawson, D Markovich
Mar 30, 2005·Behavioural Brain Research·Paul Anthony DawsonDaniel Markovich
May 25, 2006·The Biochemical Journal·Fabio PecoraAntonio Rossi
May 27, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Soohyun LeeDaniel Markovich
Jun 30, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Yazen Alnouti, Curtis D Klaassen
Jul 26, 2008·PLoS Genetics·Aurélie ClémentHenry H Roehl
Sep 16, 2008·The Journal of Steroid Biochemistry and Molecular Biology·Paul Anthony DawsonDaniel Markovich

❮ Previous
Next ❯

Citations

Apr 30, 2016·Pflügers Archiv : European journal of physiology·Meng WuSeth L Alper
May 10, 2019·Animals : an Open Access Journal From MDPI·Micol BertocchiPaolo Trevisi
Dec 8, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Anne M KoningHarry van Goor
Sep 29, 2019·Journal of Autism and Developmental Disorders·Richard J Williams
Apr 20, 2018·Physiological Reports·Adrian PostStephan J L Bakker

❮ Previous
Next ❯

Methods Mentioned

BETA
sulphotransferases
sulphotransferase

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Reproduction : the Official Journal of the Society for the Study of Fertility
Paul A Dawson
Seminars in Cell & Developmental Biology
Paul A Dawson
Critical Reviews in Clinical Laboratory Sciences
M E Morris, K Sagawa
Boletín médico del Hospital Infantil de México
H R MendozaM Haché
© 2022 Meta ULC. All rights reserved