Sulpiride induced torsade de pointes

International Journal of Cardiology
Bien-Hsien HuangChung-Yin Chen


Antipsychotic agents are known to be associated with a long QT interval and torsade de pointes. We report a 69 year old female who suffered from a syncopal attack at a psychiatric hospital and was referred to our center. Torsade de pointes with a long QT interval (QTc=680 ms) was observed on the 12 lead ECG in the emergency department and intensive care unit. A careful drug history revealed that sulpiride was the culprit agent. After stopping the medication, the QT interval returned to normal (420 ms). The patients taking sulpiride should be closely monitored, especially when it is used in combination with other antidepressant agents.


Feb 1, 1995·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·A MucciM Maj
Jun 9, 1999·The American Journal of Psychiatry·J L Levenson
Jul 20, 2002·Journal of Cardiovascular Pharmacology·Atsushi SugiyamaKeitaro Hashimoto

❮ Previous
Next ❯


Apr 10, 2010·Expert Opinion on Drug Safety·Pamela L SmithburgerSandra L Kane-Gill
Oct 28, 2009·The American Journal of Emergency Medicine·Jia-How ChangCheng-Chung Fang
Jan 15, 2008·International Journal of Cardiology·P NisseM Mathieu-Nolf
Jun 24, 2009·International Journal of Toxicology·Hyang-Ae LeeEun-Joo Kim
Nov 26, 2009·Drugs & Aging·W Victor R ViewegAnand K Pandurangi
Dec 18, 2010·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Su-Hyun Jo, So-Young Lee
Nov 25, 2011·Deutsches Ärzteblatt International·Katharina Wenzel-SeifertEkkehard Haen

❮ Previous
Next ❯

Related Concepts

Related Feeds


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Related Papers

The American Journal of Emergency Medicine
Jia-How ChangCheng-Chung Fang
International Journal of Cardiology
M Casey FlanaganMark C P Haigney
International Journal of Cardiology
M A JamesJ Vann Jones
© 2021 Meta ULC. All rights reserved