Sumatriptan (oral route of administration) for acute migraine attacks in adults.

The Cochrane Database of Systematic Reviews
Christopher J DerryR Andrew Moore

Abstract

Migraine is a highly disabling condition for the individual and also has wide-reaching implications for society, healthcare services, and the economy. Sumatriptan is an abortive medication for migraine attacks, belonging to the triptan family. To determine the efficacy and tolerability of oral sumatriptan compared to placebo and other active interventions in the treatment of acute migraine attacks in adults. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, online databases, and reference lists for studies through 13 October 2011. We included randomised, double-blind, placebo- and/or active-controlled studies using oral sumatriptan to treat a migraine headache episode, with at least 10 participants per treatment arm. Two review authors independently assessed trial quality and extracted data. We used numbers of participants achieving each outcome to calculate relative risk (or 'risk ratio') and numbers needed to treat to benefit (NNT) or harm (NNH) compared to placebo or a different active treatment. Sixty-one studies (37,250 participants) compared oral sumatriptan with placebo or an active comparator. Most of the data were for the 50 mg and 100 mg doses. Sumatriptan surpassed placebo for...Continue Reading

References

Feb 1, 1992·Cephalalgia : an International Journal of Headache·M Banerjee, L J Findley
Sep 28, 1991·Lancet·P J GoadsbyJ W Lance
Aug 1, 1987·Annals of Internal Medicine·K A L'AbbéK O'Rourke
Oct 1, 1994·Cephalalgia : an International Journal of Headache·M D FerrariG Nappi
Feb 18, 1995·BMJ : British Medical Journal·R J Cook, D L Sackett
Sep 1, 1994·Archives of Family Medicine·R K CadyT W Littlejohn
Jan 1, 1994·Journal of Neurology·G NappiO Zerbini
May 1, 1994·The American Journal of Emergency Medicine·E Hay
May 1, 1993·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·J EdmeadsT J Murray
Feb 1, 1996·Controlled Clinical Trials·A R JadadH J McQuay
Jan 1, 1996·QJM : Monthly Journal of the Association of Physicians·C E ClarkeN E Wells
Aug 1, 1996·QJM : Monthly Journal of the Association of Physicians·R J ScottG I McLaren
Oct 1, 1996·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·C J GirmanJ Waldstreicher
Oct 6, 1997·BMJ : British Medical Journal·M R TramèrH J McQuay
Dec 8, 1996·PharmacoEconomics·G D Solomon, K L Price
May 7, 1998·PharmacoEconomics·M D Ferrari
Apr 29, 1999·Archives of Internal Medicine·X H HuM L Berger
May 19, 2000·Cephalalgia : an International Journal of Headache·G GeraudR Sweet
Feb 13, 2001·Cephalalgia : an International Journal of Headache·P Tfelt-HansenUNKNOWN International Headache Society Clinical Trials Subcommittee
Mar 17, 2001·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·M J GawelA Maggisano
Apr 5, 2001·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·G BussoneC Benassuti

❮ Previous
Next ❯

Citations

Apr 15, 2015·The Journal of Headache and Pain·Mattias LindeDan Chisholm
Feb 18, 2012·The Cochrane Database of Systematic Reviews·Christopher J DerryR Andrew Moore
Apr 21, 2016·The Cochrane Database of Systematic Reviews·Simon LawR Andrew Moore
May 23, 2014·The Cochrane Database of Systematic Reviews·Sarah BirdR Andrew Moore
Oct 22, 2013·The Cochrane Database of Systematic Reviews·Simon LawR Andrew Moore
May 2, 2013·The Cochrane Database of Systematic Reviews·Sheena Derry, R Andrew Moore
May 2, 2013·The Cochrane Database of Systematic Reviews·Varo KirthiR Andrew Moore
May 2, 2013·The Cochrane Database of Systematic Reviews·Roy RabbieR Andrew Moore
Feb 27, 2019·Cephalalgia : an International Journal of Headache·Hans-Christoph DienerUNKNOWN International Headache Society Clinical Trials Standing Committee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Related Papers

The Cochrane Database of Systematic Reviews
Christopher J DerryR Andrew Moore
The Cochrane Database of Systematic Reviews
Christopher J DerryR Andrew Moore
The Cochrane Database of Systematic Reviews
Christopher J DerryR Andrew Moore
The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
Susan E JelinskiScott D Simpson
© 2022 Meta ULC. All rights reserved