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SumHer better estimates the SNP heritability of complex traits from summary statistics

Nature Genetics

Feb 3, 2019

Doug Speed, David J. Balding

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Abstract

We present SumHer, software for estimating confounding bias, SNP heritability, enrichments of heritability and genetic correlations using summary statistics from genome-wide association studies. The key difference between SumHer and the existing software LD Score Regression (LDSC) is th...read more

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  • SumHer better estimates the SNP heritability of complex traits from summary statistics

    Nature Genetics

    Feb 3, 2019

    Doug Speed, David J. Balding

    PMID: 30510236

    DOI: 10.1038/s41588-018-0279-5

    Abstract

    We present SumHer, software for estimating confounding bias, SNP heritability, enrichments of heritability and genetic correlations using summary statistics from genome-wide association studies. The key difference between SumHer and the existing software LD Score Regression (LDSC) is th...read more

    161
    68
    1

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