PMID: 9160021May 1, 1997Paper

Sun exposure and age-related macular degeneration. An Australian case-control study

Ophthalmology
P DarzinsR F Heller

Abstract

The notion that sun exposure is a risk factor for age-related macular degeneration (AMD) is widespread, but studies have not shown this conclusively. To test the hypothesis that AMD cases have greater ocular sun exposure than control subjects, the authors compared 409 cases with 286 control subjects resident in Newcastle, Australia. Sensitivity to sun and glare of the participants was characterized. Sun exposure was estimated from detailed histories and was validated against sun-seeking or avoidance behavior expected, given sun sensitivity and history of treatment for skin neoplasia. Contrary to the authors' hypothesis, control subjects had greater median annual ocular sun exposure (865 hours) than cases (723 hours), Mann-Whitney U (U) = 45704, z = -4.9, P > 0.0001. Cases had poorer tanning than did control subjects (mean 2 = 18.2, 4 df, P = 0.001) and as young adults were more sensitive to glare, odds ratio (OR), 2.5; 95% confidence intervals (CIs), 1.8 to 3.5. After stratifying by tanning ability, in the poor-tanning group, the median annual sun exposure of control subjects (685 hours) exceeded that of cases (619 hours), U = 6556, z = -1.9, P = 0.06. Among people who tanned well, control subjects also had significantly greate...Continue Reading

References

Dec 1, 1988·The New England Journal of Medicine·H R TaylorE A Emmett
Jun 1, 1988·Archives of Dermatology·T B Fitzpatrick
Apr 1, 1983·The British Journal of Ophthalmology·I M GhafourW S Foulds

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Citations

May 15, 2001·International Journal of Cancer. Journal International Du Cancer·C M VajdicB K Armstrong
Feb 27, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kourous A RezaiKasra A Rezaei
Feb 22, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Shani GolanAnat Loewenstein
Jul 31, 2007·Human Genetics·Andrew Lotery, Dorothy Trump
Sep 24, 2010·International Ophthalmology·Ian Yat Hin WongClement Wai Nang Chan
Jan 22, 2010·Journal of Genetics·Saritha KattaSubhabrata Chakrabarti
Mar 8, 2005·Survey of Ophthalmology·Shazia S AhmedDennis M Marcus
Oct 18, 2000·Survey of Ophthalmology·S BeattyM Boulton
May 15, 2003·Survey of Ophthalmology·Jayakrishna AmbatiAnthony P Adamis
Dec 18, 2001·Journal of Photochemistry and Photobiology. B, Biology·M BoultonB Rózanowski
Feb 15, 2001·Progress in Retinal and Eye Research·J R Evans
Feb 27, 2003·Progress in Retinal and Eye Research·Tos T J M BerendschotDirk van Norren
Oct 21, 2010·Expert Reviews in Molecular Medicine·Sam Khandhadia, Andrew Lotery
Oct 6, 2010·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·A R WielgusJ E Roberts
Apr 13, 2001·Journal of the American Geriatrics Society·G R Watson
Dec 4, 2004·International Ophthalmology Clinics·Johanna M Seddon, Clara A Chen
Jan 6, 2006·Retina·Carolyn Glazer-Hockstein, Joshua L Dunaief
Mar 23, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jilin Zhou, Janet R Sparrow
Jan 24, 2007·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Robert A Weale
Jan 5, 2008·Photochemistry and Photobiology·Jilin ZhouJanet R Sparrow
May 16, 2012·Photochemistry and Photobiology·Albert R Wielgus, Joan E Roberts
Apr 13, 2002·Drugs & Aging·Morten la CourMogens Holst Nissen
Jun 1, 2013·International Ophthalmology·Jason C S Yam, Alvin K H Kwok
Nov 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·Brandon-Luke L SeagleJames R Norris
Jul 24, 2001·The British Journal of Ophthalmology·C G SauerB H Weber
Mar 19, 2003·The British Journal of Ophthalmology·M MiyazakiY Nose
Feb 9, 2000·Journal of Medical Genetics·J R Yates, A T Moore
Dec 9, 2003·The British Journal of Ophthalmology·M A Mainster, J R Sparrow
Jun 1, 2005·The British Journal of Ophthalmology·G B ArdenR O Schlingemann
Dec 20, 2005·The British Journal of Ophthalmology·J C KhanUNKNOWN Genetic Factors in AMD Study
May 23, 2006·The British Journal of Ophthalmology·M A Mainster
May 10, 2007·Postgraduate Medical Journal·Brid MorrisBaljean Dhillon
Apr 29, 2008·The British Journal of Ophthalmology·M HirakawaT Sakamoto
Apr 13, 2011·Archives of Ophthalmology·Amy E MillenUNKNOWN CAREDS Study Group
May 5, 2005·Current Opinion in Ophthalmology·Bradley T SmithAllen C Ho
Dec 13, 2006·Current Opinion in Ophthalmology·Jignesh I Patel
Jul 28, 2012·American Journal of Ophthalmology·Jordana K SchmierEdmund C Lau
May 4, 2011·Journal of the American Academy of Dermatology·Daniel P WalkerCheryl Lee D Eberting
Feb 10, 2010·Ophthalmology·Martin A Mainster, Patricia L Turner

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