SUNCT syndrome: Short-lasting Unilateral Neuralgiform headache with Conjunctival injection and Tearing

Seminars in Ophthalmology
Patrick L AloreMícheál P Macken

Abstract

The SUNCT syndrome refers to Short-lasting Unilateral Neuralgiform headache with Conjunctival injection and Tearing. It is characterized by brief attacks of severe unilateral pain in the orbitotemporal region, associated with ipsilateral cranial autonomic disturbances. All SUNCT patients experience ipsilateral conjunctival injection and lacrimation. Mean age of onset is 50 years with a male predominance. The syndrome is often misdiagnosed as trigeminal neuralgia or cluster headache. Primary and secondary forms exist, the secondary form is most commonly associated with lesions of the posterior fossa or pituitary adenoma. The SUNCT syndrome is refractory to most commonly employed therapies. Lamotrigine has recently been reported as an effective first line therapy.

References

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Jun 2, 2005·Annals of Neurology·Massimo LeoneGennaro Bussone

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Citations

May 17, 2011·Journal of Neurosurgery·H Neil Simms, Christopher R Honey
Aug 11, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Gary D Klasser, Ramesh Balasubramaniam
Dec 17, 2008·Headache·Jeong-Yoon ChoiSung-Wook Yu
Apr 30, 2013·Cephalalgia : an International Journal of Headache·Daniel Y H TanJohn Thomas

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