SunGold Kiwifruit Supplementation of Individuals with Prediabetes Alters Gut Microbiota and Improves Vitamin C Status, Anthropometric and Clinical Markers

Nutrients
Renée WilsonAnitra Carr

Abstract

Kiwifruit are a nutrient dense food and an excellent source of vitamin C. Supplementation of the diet with kiwifruit enhances plasma vitamin C status and epidemiological studies have shown an association between vitamin C status and reduced insulin resistance and improved blood glucose control. In vitro experiments suggest that eating kiwifruit might induce changes to microbiota composition and function; however, human studies to confirm these findings are lacking. The aim of this study was to investigate the effect of consuming two SunGold kiwifruit per day over 12 weeks on vitamin C status, clinical and anthropometric measures and faecal microbiota composition in people with prediabetes. This pilot intervention trial compared baseline measurements with those following the intervention. Participants completed a physical activity questionnaire and a three-day estimated food diary at baseline and on completion of the trial. Venous blood samples were collected at each study visit (baseline, 6, 12 weeks) for determination of glycaemic indices, plasma vitamin C concentrations, hormones, lipid profiles and high-sensitivity C-reactive protein. Participants provided a faecal sample at each study visit. DNA was extracted from the faeca...Continue Reading

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Citations

Aug 6, 2020·Nutrients·Alicja Ewa RatajczakIwona Krela-Kaźmierczak
Oct 3, 2020·Nutrients·Jun Wern YauAmutha Ramadas
Mar 1, 2019·Nutrients·Omorogieva Ojo
Dec 31, 2020·Microorganisms·Agnieszka ZawadaIwona Krela-Kaźmierczak
Jan 12, 2021·Frontiers in Nutrition·Elvira VerduciAnnalisa Terranegra
Oct 17, 2020·Journal of Translational Internal Medicine·Qiongrong HuangZhiyuan Hu
Jul 7, 2021·Journal of the Academy of Nutrition and Dietetics·Cara L FrankenfeldJohanna W Lampe
May 21, 2021·The Journal of Clinical Endocrinology and Metabolism·Ping HuAn Pan
Sep 11, 2021·Food & Function·Zoi KatsirmaKevin Whelan

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Methods Mentioned

BETA
ELISA

Software Mentioned

IPAQ
Unifrac
BLAST
Kaiculator

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