PMID: 6967495Jul 1, 1980Paper

Sunscreens prevent ultraviolet photocarcinogenesis

Journal of the American Academy of Dermatology
L H KligmanA M Kligman

Abstract

Sunscreens of low or high sun protection factors (SPF*) were tested for their ability to inhibit ultraviolet (UV) carcinogenesis in two varieties of hairless mice. Low protection (SPF = 2) reduced by 50% the number of albino animals developing tumors. High protection (SPF =15) prevented tumor formation. Tumorigenesis was totally prevented in the lightly pigmented variety with either sunscreen, demonstrating the added protection of melanin. In mice and man, UV-induced cancer is a cumulative process. Reducing the amount of UV light reaching the basal layer will retard that process.

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Citations

Jan 1, 1981·Archives of Dermatological Research·L H Kligman, A M Kligman
Jan 1, 1990·Archives of Dermatological Research·H Flindt-HansenT E Larsen
Jun 16, 2010·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·C Esser, J Krutmann
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