Super-early images of brain perfusion SPECT using 123 I-IMP for the assessment of hyperperfusion in stroke patients

Annals of Nuclear Medicine
Yusuke InoueYutaka Abe

Abstract

With the advancement of reperfusion therapy in stroke patients, assessment of perfusion status after therapy is gaining importance. Hyperperfusion tends to be underestimated by the conventional early imaging of 123I-IMP brain perfusion SPECT. We evaluated the utility of super-early imaging as an adjunct to early imaging for the assessment of postischemic hyperperfusion in stroke patients. Sixty-seven patients who underwent 123I-IMP brain perfusion SPECT within 14 days after the onset of cerebral infarction were retrospectively analyzed. Super-early (4-10 min) and early (15-45 min) images were acquired using a dual-headed gamma camera. Postischemic hyperperfusion was visually assessed using the early images alone and then using both the super-early and early images, and the frequency of postischemic hyperperfusion and the confidence level of the judgement were evaluated. For quantitative evaluation of image contrast, the contrast ratios (the count ratios of the hyperperfused to normal areas) were calculated. The frequency of postischemic hyperperfusion was significantly higher using both the super-early and early images (28/67 patients) than using the early images alone (17/67 patients, p < 0.001). In 56 patients in whom judgeme...Continue Reading

References

Jan 1, 1990·European Journal of Nuclear Medicine·J L MorettiB L Holman
Sep 1, 1993·Clinical Nuclear Medicine·H MatsudaJ Yamashita
Feb 20, 2002·Clinical Nuclear Medicine·Kunio OkamotoTsunehiko Nishimura
Dec 15, 2007·Journal of Neurosurgery·Kuniaki OgasawaraUNKNOWN Japanese Society for Treatment at Neck in Cerebrovascular Disease Study Group
May 30, 2009·Stroke; a Journal of Cerebral Circulation·Deidre A De SilvaUNKNOWN Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators
Jul 9, 2010·Brain & Development·Hiromichi ItoShoji Kagami
Sep 21, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Takeo AbumiyaKiyohiro Houkin
Jan 8, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Songlin YuUNKNOWN UCLA Stroke Investigators
Jul 1, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Shuhei OkazakiMasafumi Ihara

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Related Papers

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Y R Tran DinhJ Seylaz
Nihon rinsho. Japanese journal of clinical medicine
H Kinoshita, K Hayashi
© 2022 Meta ULC. All rights reserved