Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study.

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Alejandra VasquezPediatric Status Epilepticus Research Group (pSERG)

Abstract

To characterize the pediatric super-refractory status epilepticus population by describing treatment variability in super-refractory status epilepticus patients and comparing relevant clinical characteristics, including outcomes, between super-refractory status epilepticus, and nonsuper-refractory status epilepticus patients. Retrospective cohort study with prospectively collected data between June 2011 and January 2019. Seventeen academic hospitals in the United States. We included patients 1 month to 21 years old presenting with convulsive refractory status epilepticus. We defined super-refractory status epilepticus as continuous or intermittent seizures lasting greater than or equal to 24 hours following initiation of continuous infusion and divided the cohort into super-refractory status epilepticus and nonsuper-refractory status epilepticus groups. None. We identified 281 patients (157 males) with a median age of 4.1 years (1.3-9.5 yr), including 31 super-refractory status epilepticus patients. Compared with nonsuper-refractory status epilepticus group, super-refractory status epilepticus patients had delayed initiation of first nonbenzodiazepine-antiseizure medication (149 min [55-491.5 min] vs 62 min [33.3-120.8 min]; p ...Continue Reading

References

Nov 1, 1990·Epilepsia·C MarescauxG Franck
Apr 1, 1995·Pediatric Neurology·B K AlldredgeD M Ferriero
Feb 15, 2002·Archives of Neurology·Stephan A MayerBrian-Fred Fitzsimmons
May 29, 2002·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·F Villani, G Avanzini
May 29, 2003·Pediatric Neurology·D Barry Sinclair
Oct 26, 2005·Neurology·K ErikssonM Koivikko
May 28, 2008·Epilepsia·Fred A Lado, Solomon L Moshé
Dec 17, 2009·Archives of Neurology·Alex D CooperAlejandro A Rabinstein
Feb 23, 2010·Revue neurologique·M-E LampinS Auvin
Dec 8, 2010·Nature Reviews. Neurology·Annamaria VezzaniTallie Z Baram
Apr 25, 2012·Neurocritical Care·Gretchen M BrophyUNKNOWN Neurocritical Care Society Status Epilepticus Guideline Writing Committee
Jan 16, 2013·JAMA Neurology·Sara E HockerAlejandro A Rabinstein
Mar 30, 2013·Critical Care Clinics·Ryan Wilkes, Robert C Tasker
Jun 12, 2013·Seminars in Fetal & Neonatal Medicine·Chakrapani Vasudevan, Malcolm Levene
Jun 12, 2013·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Rune SortPeter Uldall
Jul 16, 2013·Current Treatment Options in Neurology·Carla Lopinto-Khoury, Michael R Sperling
Nov 30, 2013·Pediatric Neurology·Sunila E O'ConnorBeth Zupec-Kania
Feb 13, 2014·Neurocritical Care·Bhavpreet S DhamFred Rincon
Apr 25, 2014·Current Neurology and Neuroscience Reports·Sara HockerW David Freeman
May 17, 2014·Journal of Clinical Epidemiology·Mark E GlickmanMark R Schultz
Jun 6, 2014·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Ryan Wilkes, Robert C Tasker
Oct 15, 2014·Acta Neurologica Scandinavica·L TianD Zhou
May 8, 2015·Neurology·Iván Sánchez FernándezUNKNOWN Pediatric Status Epilepticus Research Group (pSERG)
Jul 5, 2015·Epilepsy & Behavior : E&B·Anne-Mari KantanenReetta Kälviäinen
Jul 7, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Ruzica KravljanacTatjana Pekmezovic
Aug 21, 2015·CNS Drugs·Vidya ChidambaranAjay D'Mello
Aug 25, 2015·Current Neurology and Neuroscience Reports·Ahmad BayrleeGretchen M Brophy
Nov 13, 2015·Critical Care : the Official Journal of the Critical Care Forum·Adéla KrajčováFrantišek Duška
Dec 3, 2015·Expert Opinion on Pharmacotherapy·Eugen TrinkaFrancesco Brigo
Apr 16, 2016·Acta Neurologica Scandinavica·L DelajA O Rossetti
Aug 1, 2016·Seizure : the Journal of the British Epilepsy Association·Brian AppavuRanda Jarrar
Aug 9, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Robert C TaskerUNKNOWN Pediatric Status Epilepticus Research Group

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