PMID: 30796865Feb 24, 2019Paper

Superficial candidosis course in patients with carbohydrate metabolism disorder and diabetes mellitus

Wiadomości lekarskie : organ Polskiego Towarzystwa Lekarskiego
Оrysya О SyzonMarianna O Dashko

Abstract

Introduction: One of the pressing issues of modern dermatology is the prevalence of diseases of skin and mucous membranes caused by yeast-like fungi. The aim: To study specific features of the course of skin and mucous membranes superficial candidosis against the background of initial carbohydrate metabolism disorders or diabetes mellitus. Materials and methods: We have examined 93 patients aged 18-75 suffering from superficial candidosis. Candidosis was diagnosed based on anamnesis data, results of clinical tests and laboratory studies. The study of carbohydrate metabolism included determining of the glucose level under fasting conditions to establish possible diabetes mellitus and glucose tolerance test (75 g glucose load), glycosylated hemoglobin (HbA1c) and fructosamine (FR). Results: In patients with mild and moderate candidosis we have detected an increased rates of НbA1с and fructosamine, as compared with the like indicators received in the control group, by 1.54 and 1.21 times respectively. In patients with severe candidosis and relapses the concentrations of НbA1с increased by 2.59 times, FR - by 2.26 times against the indicators received in the control group. Thus, increased levels of blood glycosylated protein indica...Continue Reading

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