Superficial femoral vein invasion by a benign neurofibroma in a non-neurofibromatosis patient: case report

Neurosurgery
Claude-Edouard ChâtillonLine Jacques

Abstract

Neurofibromas are benign neural sheath tumors arising from intraneural supporting cells. Such tumors are characteristic of neurofibromatosis Type I (von Recklinghausen disease) but also occur sporadically. Vascular involvement by neurofibromata is rare, but has been described in the past in the context of neurofibromatosis. There is, to our knowledge, no description of vascular involvement by a neurofibroma in a non-neurofibromatosis patient. A 40-year-old woman presented with a 4 year history of a right thigh mass associated with diffuse lower extremity pain. She had no other clinical manifestations of neurofibromatosis and no known family member with neurofibromatosis Type I. Magnetic resonance imaging scans revealed a well-defined solid mass in the anteromedial aspect of the right thigh closely associated with the superficial femoral vein. The vessel segment and encapsulated mass were resected "en bloc" after proximal and distal ligation of the vein. The pathological appearance of the mass was consistent with a benign neurofibroma that had infiltrated all layers of the vessel. Vessel invasion by a benign sporadic neurofibroma is a rare occurrence with potentially severe implications for the patient. It suggests that surgical...Continue Reading

References

May 2, 2001·Journal of Vascular Surgery·L P YoungJ O Menzoian

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Citations

Jul 3, 2009·Journal of Neurosurgery. Spine·Liqun YangCraig Winter
Nov 3, 2009·Journal of Neurosurgery. Pediatrics·Anthony A FigajiJonathan C Peter
Jul 7, 2007·Neurosurgical Focus·Roberto GazzeriGiovanni Gazzeri
Nov 2, 2011·The American Journal of Dermatopathology·Sudeep GaudiMichael B Morgan
May 28, 2019·Postgraduate Medical Journal·Shuzhong LiuYong Liu

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