Superior exercise performance in lifelong Tibetan residents of 4,400 m compared with Tibetan residents of 3,658 m

American Journal of Physical Anthropology
L S CurranL G Moore

Abstract

Few environments challenge human populations more than high altitude, since the accompanying low oxygen pressures (hypoxia) are pervasive and impervious to cultural modification. Work capacity is an important factor in a population's ability to thrive in such an environment. The performance of work or exercise is a measure of the integrated functioning of the O2 transport system, with maximal O2 uptake (.VO2max) a convenient index of that function. Hypoxia limits the ability to transport oxygen: maximal O2 uptake decreases with ascent to high altitude, and years of high altitude residence do not restore sea level .VO2max values. Since Tibetans live and work at some of the highest altitudes in the world, their ability to exercise at very high altitude (>4,000 m) may define the limits of human adaptation to hypoxia. We transported 20 Tibetan lifelong residents of > or =4,400 m down to 3,658 m in order to compare them with 16 previously studied Tibetan residents of Lhasa (3,658 m). The two groups of Tibetans were matched for age, weight, and height. All studies were performed in Lhasa within 3 days of the 4,400 m Tibetans' arrival. Standard test protocol and criteria were used for attaining .VO2max on a Monark bicycle ergometer, w...Continue Reading

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Citations

Feb 4, 2014·Extreme Physiology & Medicine·Deirdre CaffreyUNKNOWN CRONICAS Cohort Study Group
Jul 10, 2001·High Altitude Medicine & Biology·L G Moore
Apr 10, 2004·High Altitude Medicine & Biology·Tom D BrutsaertHilde Spielvogel
Jun 13, 2006·High Altitude Medicine & Biology·Claudio MarconiPaolo Cerretelli
Sep 19, 2006·High Altitude Medicine & Biology·Tianyi Wu, Bengt Kayser
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Jun 2, 2009·High Altitude Medicine & Biology·Paolo CerretelliClaudio Marconi
May 8, 2008·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Tom D Brutsaert
Sep 24, 2005·The Journal of Physiology·Claudio MarconiPaolo Cerretelli
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Jun 10, 2016·High Altitude Medicine & Biology·Jui-Lin Fan, Bengt Kayser
Jan 9, 1999·American Journal of Physical Anthropology·L G MooreS Zamudio
Nov 12, 2014·American Journal of Physical Anthropology·Melisa KiyamuTom D Brutsaert
Jan 17, 2019·High Altitude Medicine & Biology·Mathew G RiegerAli M McManus
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Dec 18, 2007·The Journal of Experimental Biology·Gregory A RussellKimberly A Hammond
Aug 26, 2021·High Altitude Medicine & Biology·Aglaia ForrerMichael Furian

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