Superior field performance of waxy corn engineered using CRISPR-Cas9

Nature Biotechnology
Huirong GaoR Bob Meeley

Abstract

We created waxy corn hybrids by CRISPR-Cas9 editing of a waxy allele in 12 elite inbred maize lines, a process that was more than a year faster than conventional trait introgression using backcrossing and marker-assisted selection. Field trials at 25 locations showed that CRISPR-waxy hybrids were agronomically superior to introgressed hybrids, producing on average 5.5 bushels per acre higher yield.

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Citations

Jun 28, 2020·The Plant Journal : for Cell and Molecular Biology·Maria Fedorova, Rod A Herman
Aug 30, 2020·The Plant Journal : for Cell and Molecular Biology·Zongyou LvWansheng Chen
May 21, 2020·Frontiers in Plant Science·Huirong GaoN Doane Chilcoat
Sep 6, 2020·Genes·Rodrigo Ribeiro Arnt Sant'AnaSarah Zanon Agapito-Tenfen
Sep 26, 2020·Nature Reviews. Molecular Cell Biology·Haocheng ZhuCaixia Gao
Jul 30, 2020·The Journal of Nutrition·Kendal D Hirschi
Aug 28, 2020·Proceedings. Biological Sciences·Julie Blommaert
Apr 25, 2021·Trends in Plant Science·Matthew ReynoldsPeter E Wittich
Mar 18, 2021·The Plant Journal : for Cell and Molecular Biology·Satoru SukegawaSeiichi Toki
May 1, 2021·International Journal of Molecular Sciences·Qier LiuMaoyun She
May 13, 2021·Plant Cell Reports·Sukumar BiswasJianxin Shi
May 6, 2021·G3 : Genes - Genomes - Genetics·Frank TechnowMark Cooper
Jan 23, 2021·Annual Review of Plant Biology·Yameng LiangFeng Tian
Jun 29, 2021·Frontiers in Plant Science·Young-Cheon KimSeonghoe Jang
Jul 16, 2021·Transgenic Research·Jerlie Mhay MatresInez H Slamet-Loedin
Jul 22, 2021·Journal of Agricultural and Food Chemistry·Shakeel AhmadShaoqing Tang
Aug 27, 2021·Annals of the New York Academy of Sciences·Jennifer CableRammyani Bagchi
Nov 2, 2021·Frontiers in Plant Science·Juliana Erika de Carvalho Teixeira YassitepePaulo Arruda

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Datasets Mentioned

BETA
MN294713
MN294714
MN294715
MN294716
MN294717
MN294719

Methods Mentioned

BETA
phosphotransferase
PCR
transgenic
genotyping

Software Mentioned

ASReml

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