PMID: 9540331Apr 16, 1998Paper

Superior sagittal sinus thrombosis associated with primary antiphospholipid syndrome--case report

Neurologia Medico-chirurgica
S NagaiA Takaku

Abstract

A 36-year-old female with a history of recurrent pregnancy loss experienced sudden onset of disturbance in consciousness, with right hemiparesis and total aphasia. Computed tomography revealed a massive hemorrhage in the left frontal lobe, and angiography showed occlusion of the anterior two-thirds of the superior sagittal sinus. Laboratory investigations detected the presence of lupus anticoagulant, elevation of the anticardiolipin beta 2-glycoprotein I complex antibody level, and a decreased protein S activity level. There were no underlying conditions, such as connective tissue disorders, malignancies, infectious diseases, and drug-induced disorders, so the diagnosis was primary antiphospholipid syndrome. Primary antiphospholipid syndrome should be considered in the evaluation of patients with "idiopathic" or "primary" sinus and cerebral venous thrombosis.

Citations

Sep 4, 2004·Neurosurgical Focus·Alfredo Quinones-HinojosaMichael T Lawton
Nov 26, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Doniel DrazinWouter Schievink
Jul 29, 2006·Magnetic Resonance Imaging Clinics of North America·Pamela W SchaeferR Gilberto Gonzalez
Dec 20, 2005·Neuroimaging Clinics of North America·Pamela W SchaeferR Gilberto Gonzalez
Dec 23, 2009·The Journal of Obstetrics and Gynaecology Research·Tharangrut HanprasertpongKittipong Riabroi
Sep 6, 2001·Rheumatic Diseases Clinics of North America·J T Merrill
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