Superoxide dismutase activity in leukocytes

The Journal of Clinical Investigation
L R DeChateletR B Johnston

Abstract

Superoxide dismutase activity has been identified in both human neutrophils and rabbit alveolar macrophages by two distinct assay procedures. The enzyme is insensitive to both cyanide and azide and is present in the cytosol of the cell. The identification of this enzyme in phagocytic cells is compatible with the theory that superoxide anion might be involved in the bactericidal activity of the cell. It is proposed that the enzyme functions to protect the cell against superoxide generated during the phagocytic process.

References

Mar 1, 1973·The Journal of Clinical Investigation·B M BabiorJ T Curnutte
May 2, 1968·The New England Journal of Medicine·R L Baehner, D G Nathan
Jun 1, 1971·Archives of Internal Medicine·J B GeeR E Basford
Jan 31, 1972·Biochemical and Biophysical Research Communications·M NishikimiK Yagi
Dec 1, 1967·The Journal of Experimental Medicine·S J Klebanoff
May 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·J M McCordI Fridovich
Aug 1, 1970·Biochemical Medicine·L R DeChatelet, M R Cooper
Oct 9, 1967·Biochimica Et Biophysica Acta·W H Evans, M Rechcigl

❮ Previous
Next ❯

Citations

Feb 8, 1979·European Journal of Pediatrics·M RisterE Gladtke
Sep 15, 1984·Experientia·M Baggiolini
Aug 9, 2003·Journal of Physiology and Biochemistry·OmAli Y El-Khawaga, M M El-Naggar
Aug 1, 1977·The Journal of Pediatrics·R R KretschmerS P Gotoff
Jan 1, 1975·The Journal of Experimental Medicine·D B Drath, M L Karnovsky
Oct 1, 1983·Annals of the Rheumatic Diseases·A A Youssef, D N Baron
Apr 1, 1980·Journal of Medical Genetics·J M BergR G Worton
Oct 1, 1974·The Journal of Clinical Investigation·M L Salin, J M McCord
Nov 1, 1975·The Journal of Clinical Investigation·I M GoldsteinG Weissmann
May 1, 1981·The Journal of Clinical Investigation·A A VoetmanD Roos
Feb 18, 2014·European Journal of Pharmacology·Ahmed TayelMohammed M H Al-Gayyar
Oct 1, 2014·Chemico-biological Interactions·Nehal M Elsherbiny, Mohamed El-Sherbiny
Jun 29, 2011·Drug Development and Industrial Pharmacy·Mohamed El-FarIbrahim M El-Sherbiny
May 29, 2012·Biochemical and Biophysical Research Communications·Entsar A Saad
Nov 26, 2015·Life Sciences·Nehal M ElsherbinyKhaled H Abd El Galil
Oct 31, 2015·Cytokine·Nehal M ElsherbinyMohammed M H Al-Gayyar
Jul 30, 2015·Redox Report : Communications in Free Radical Research·Mohammed M H Al-GayyarAmany A El-Hawwary
Mar 3, 2007·The Journal of Pharmacy and Pharmacology·Mohammed M H Al-GayyarAmal M El-Gayar
Jul 1, 1979·The Journal of Surgical Research·M M FuenferH C Polk
Jun 20, 2014·Redox Report : Communications in Free Radical Research·I O Sherif, M M Al-Gayyar
Jul 19, 2013·Pharmaceutical Biology·Mohamed F SalamaMohammed M H Al-Gayyar
May 14, 1979·Biochemical and Biophysical Research Communications·R Gennaro, D Romeo
Feb 1, 1977·Archives of Biochemistry and Biophysics·T J Van BerkelJ F Koster
Jun 28, 2017·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Shimaa M HassounMamdouh M El-Shishtawy
Sep 1, 1978·CRC Critical Reviews in Toxicology·M N Walters, J M Papadimitriou
Apr 23, 2020·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Eman Salah El-Shafey, Eslam Samy Elsherbiny
Mar 15, 2017·MedChemComm·Entsar A SaadNada M ELmenawy
Sep 24, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shadia A ElsayedCharles J Walsby
Aug 1, 1975·Infection and Immunity·S S KaplanR E Basford
May 24, 1991·Cancer Letters·J K KweeO R Affonso
Mar 1, 1981·The Journal of Investigative Dermatology·J B SedgwickE R Hurd

❮ Previous
Next ❯

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