Supervised exercise training as an adjunct therapy for venous leg ulcers: a randomized controlled feasibility trial.

The British Journal of Dermatology
Markos KlonizakisJonathan Michaels

Abstract

Venous leg ulcers (VLUs) are typically painful and heal slowly. Compression therapy offers high healing rates; however, improvements are not usually sustained. Exercise is a low-cost, low-risk and effective strategy for improving physical and mental health. Little is known about the feasibility and efficacy of supervised exercise training used in combination with compression therapy patients with VLUs. To assess the feasibility of a 12-week supervised exercise programme as an adjunct therapy to compression in patients with VLUs. This was a two-centre, two-arm, parallel-group, randomized feasibility trial. Thirty-nine patients with venous ulcers were recruited and randomized 1 : 1 either to exercise (three sessions weekly) plus compression therapy or compression only. Progress/success criteria included exercise attendance rate, loss to follow-up and patient preference. Baseline assessments were repeated at 12 weeks, 6 months and 1 year, with healing rate and time, ulcer recurrence and infection incidents documented. Intervention and healthcare utilization costs were calculated. Qualitative data were collected to assess participants' experiences. Seventy-two per cent of the exercise group participants attended all scheduled exerc...Continue Reading

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Citations

May 23, 2018·The British Journal of Dermatology·A Ferris, K Harding
Apr 27, 2019·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Victoria TeamCarolina D Weller
Dec 5, 2017·European Journal of Applied Physiology·Garry A TewMarkos Klonizakis
Oct 6, 2020·Frontiers in Physiology·Helena LenasiMarkos Klonizakis
Jan 22, 2021·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Markus Stücker
Oct 30, 2020·Alimentary Pharmacology & Therapeutics·Katherine JonesGarry A Tew
Mar 12, 2021·Cardiology and Therapy·Vwaire OrhurhuDua Anahita
Aug 31, 2021·Jornal Vascular Brasileiro·Ana Carla SchmidtRicardo Zanetti Gomes
Nov 3, 2021·The British Journal of Dermatology·D C Bosanquet, K G Harding

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Clinical Trials Mentioned

ISRCTN10205425

Software Mentioned

SPSS

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