Suplatast tosilate for treating cutaneous mastocytosis

Pediatric Dermatology
Hiroki YasudoAkira Oka

Abstract

Pediatric cutaneous mastocytosis is a rare disease caused by mast cell hyperplasia. We report the case of an infant diagnosed as cutaneous mastocytosis and seasonal allergies. The wheals, flushing, and pruritus of the mastocytosis were unresponsive to combination therapy with an antihistamine, a mast cell stabilizer (sodium cromoglycate), and a leukotriene antagonist. Addition of suplatast tosilate as a treatment for the seasonal allergy also dramatically improved his cutaneous symptoms and signs. Further trials of suplatast tosilate in selected cases of cutaneous mastocytosis are warranted.

References

Mar 27, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·H Kimata
Jan 1, 2014·Pediatric Allergy, Immunology, and Pulmonology·Marianne Frieri, Mahvish Quershi

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Citations

Nov 21, 2018·International Journal of Dermatology·Moriaki Nishihira, Hiroyuki Miura

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