Supplemental Vitamins and Minerals for CVD Prevention and Treatment

Journal of the American College of Cardiology
David J A JenkinsJohn L Sievenpiper

Abstract

The authors identified individual randomized controlled trials from previous meta-analyses and additional searches, and then performed meta-analyses on cardiovascular disease outcomes and all-cause mortality. The authors assessed publications from 2012, both before and including the U.S. Preventive Service Task Force review. Their systematic reviews and meta-analyses showed generally moderate- or low-quality evidence for preventive benefits (folic acid for total cardiovascular disease, folic acid and B-vitamins for stroke), no effect (multivitamins, vitamins C, D, β-carotene, calcium, and selenium), or increased risk (antioxidant mixtures and niacin [with a statin] for all-cause mortality). Conclusive evidence for the benefit of any supplement across all dietary backgrounds (including deficiency and sufficiency) was not demonstrated; therefore, any benefits seen must be balanced against possible risks.

Citations

Sep 14, 2018·Journal of Applied Physiology·Matthew J RossmanDouglas R Seals
Jul 5, 2019·British Journal of Pharmacology·Francesco VisioliJoao Tomé-Carneiro
Jan 30, 2020·Circulation·Salim S ViraniUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Jun 7, 2019·JAAPA : Official Journal of the American Academy of Physician Assistants·Matthew J StinsonAnna Carrigan
Mar 12, 2020·Nutrition & Dietetics : the Journal of the Dietitians Association of Australia·Arpita DasVasant Hirani
Feb 28, 2020·Neurology·J David Spence, Christy Tangney
Apr 24, 2020·Journal of Cardiovascular Pharmacology and Therapeutics·Erfan TasdighiMahnoosh Foroughi
Sep 10, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Joseph FirthJerome Sarris
Jan 11, 2020·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Lina Peña-AcevedoAlexander Aristizabal-Solis
Jul 8, 2020·Nutrients·Alessandra VezzoliRoberto Accinni
Dec 7, 2019·BMJ Evidence-based Medicine·J David Spence
Mar 20, 2019·Nutrients·J David Spence
May 10, 2019·Frontiers in Immunology·Ana María Ruiz-LeónRosa Casas
May 25, 2020·Clinical Rheumatology·Albani Eleni, Petrou Panagiotis
Feb 13, 2019·European Journal of Epidemiology·John P A Ioannidis
Feb 13, 2020·Frontiers in Pharmacology·Melania Maria SerafiniCristina Lanni
Jul 1, 2020·BMJ : British Medical Journal·Fang Fang ZhangJeffrey B Blumberg
Feb 19, 2020·Current Cardiology Reports·David Perez InglesHernando Garcia
Nov 16, 2018·Psychology & Health·Douglas MacFarlaneUllrich K H Ecker
Sep 15, 2020·Rejuvenation Research·Grant A RutledgeMahtab Jafari
Dec 23, 2020·Stroke; a Journal of Cerebral Circulation·Kathrine J VinknesFumiaki Imamura
Jan 9, 2021·Journal of the American College of Cardiology·Jiao LuoRaymond Noordam
Jul 17, 2019·Clinical Therapeutics·Heitor O SantosRodrigo C O Macedo
Jan 28, 2021·Circulation·Salim S ViraniUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Feb 6, 2020·Deutsches Ärzteblatt International·Alexandra JungertSabine Rohrmann
Dec 9, 2020·Antioxidants·Antonio J AmorIolanda Lázaro
Jan 30, 2021·Journal of the American College of Cardiology·Erin D MichosLawrence J Appel
Dec 10, 2020·International Journal of Mental Health Systems·C EeJ Sarris
Jan 30, 2021·Journal of the American College of Cardiology·David J A JenkinsJohn L Sievenpiper

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Related Papers

Nutrition in Clinical Care : an Official Publication of Tufts University
U. S. Preventive Services Task Force
The American Journal of Medicine
Abhishek DeshpandeMichael B Rothberg
JAMA : the Journal of the American Medical Association
Eva M Lonn
© 2022 Meta ULC. All rights reserved