Suppressing bacterial interaction with copper surfaces through graphene and hexagonal-boron nitride coatings

ACS Applied Materials & Interfaces
Carolina ParraPatricio Häberle

Abstract

Understanding biological interaction with graphene and hexagonal-boron nitride (h-BN) membranes has become essential for the incorporation of these unique materials in contact with living organisms. Previous reports show contradictions regarding the bacterial interaction with graphene sheets on metals. Here, we present a comprehensive study of the interaction of bacteria with copper substrates coated with single-layer graphene and h-BN. Our results demonstrate that such graphitic coatings substantially suppress interaction between bacteria and underlying Cu substrates, acting as an effective barrier to prevent physical contact. Bacteria do not "feel" the strong antibacterial effect of Cu, and the substrate does not suffer biocorrosion due to bacteria contact. Effectiveness of these systems as barriers can be understood in terms of graphene and h-BN impermeability to transfer Cu(2+) ions, even when graphene and h-BN domain boundary defects are present. Our results seem to indicate that as-grown graphene and h-BN films could successfully protect metals, preventing their corrosion in biological and medical applications.

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Citations

Dec 10, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Samuel BernardPhilippe Miele
Nov 18, 2015·Journal of Nanobiotechnology·Carolina ParraPatricio Villalobos
Dec 14, 2017·Journal of Nanobiotechnology·Agnese BregnocchiMaria Sabrina Sarto
Jul 31, 2018·Biomaterials Science·A MerloI Mijakovic
Feb 16, 2021·Frontiers in Bioengineering and Biotechnology·João SantosAndrea Capasso
Feb 3, 2021·Colloids and Surfaces. B, Biointerfaces·Guihua CaoJianbin Guo
Dec 20, 2020·Colloids and Surfaces. B, Biointerfaces·Tahereh Seifi, Ali Reza Kamali
Apr 19, 2021·Colloids and Surfaces. B, Biointerfaces·Xuejie XieRuhong Zhou
Feb 13, 2018·ACS Nano·Govinda ChilkoorVenkataramana Gadhamshetty
Oct 27, 2020·ACS Nano·Govind ChilkoorVenkataramana Gadhamshetty

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