Suppression of ovarian function by Microgynon 30 in day 1 and day 5 "starters"

Contraception
D R TaylorK J Dennis

Abstract

The suppression of ovulation during the first treatment cycle with Microgynon 30 (150 micrograms levonorgestrel and 30 micrograms ethinyl oestradiol) for nine subjects starting the "pill" on day 1 of their cycle and five subjects on day 5 was investigated. Serum oestradiol and progesterone levels throughout the cycle and midcycle urinary LH levels were reliably suppressed in all day 1 "starters". Serum progesterone levels and urinary LH levels were also suppressed in day 5 "starters" but one subject produced oestradiol levels within the normal range of ovulatory cycles. Mean oestradiol levels of day 5 "starters" were found to be significantly higher than those of day 1 "starters" (p less than 0.05).

References

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Jul 13, 1985·British Medical Journal
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Citations

Mar 1, 1997·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·T RabeB Runnebaum
Nov 17, 2012·Contraception·Dalia Brahmi, Kathryn M Curtis
Jan 18, 2006·Contraception·Kathryn M CurtisHerbert B Peterson
Oct 17, 2018·Expert Review of Clinical Pharmacology·Carlo BastianelliGiuseppe Benagiano
Sep 19, 2020·Pharmacology Research & Perspectives·Jan de JongPeter Hellemans

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