PMID: 3748466Aug 15, 1986Paper

Suprachiasmatic nucleus transplants function as an endogenous oscillator only in constant darkness

Neuroscience Letters
R Aguilar-RobleroR Drucker-Colín

Abstract

Rats which sustained lesions of the suprachiasmatic nucleus (SCN) were transplanted with fetal hypothalamic tissue which included the SCN. After the graft, animals were kept under a 12:12 light-dark (LD) cycle during 6 weeks at which time half the animals were placed in constant light (LL) and half in constant darkness (DD). The results showed that all grafted rats recovered the photoperiod under LD, but under constant conditions rats began to free-run only in DD. The results suggest that the grafted tissue functions as a self-sustained oscillator only in darkness.

References

Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·S T Inouye, H Kawamura
Oct 1, 1979·Cell and Tissue Research·K Dierickx, F Vandesande
Jun 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·F K Stephan, I Zucker
Oct 8, 1984·Brain Research·R Drucker-ColínF Bermudez Rattoni
Oct 1, 1983·Physiology & Behavior·C Eastman, A Rechtschaffen
Sep 5, 1983·Brain Research·W J SchwartzM C Moore-Ede
Jan 1, 1980·The Journal of Comparative Neurology·W J SchwartzC B Smith

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Citations

Jan 1, 1992·Pharmacology & Therapeutics·W J Rietveld
Dec 1, 1990·Brain Research. Developmental Brain Research·M T Romero, R Silver
Jul 25, 2007·Progress in Neurobiology·Timothy M Brown, Hugh D Piggins
Mar 12, 1993·Brain Research·R Aguilar-Roblero, A Vega-González
Aug 1, 1992·Chronobiology International·R Aguilar-RobleroR Y Moore
Jun 1, 1996·Journal of Biological Rhythms·S MatsumotoE L Bittman
May 18, 2018·Frontiers in Neural Circuits·Wojciech KrzeptowskiElżbieta Pyza
Jan 1, 1992·Cell Transplantation·D F EmerichP R Sanberg
Feb 1, 2021·Experimental Gerontology·Fabian-Xosé FernandezDavid C Negelspach

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