Supragenotypic groups of the hepatitis B virus genome

The Journal of General Virology
Michael A PurdyYury Khudyakov

Abstract

Phylogenetic relationships among hepatitis B virus (HBV) genotypes were investigated using different regions across the genome. The phylogenetic analysis in conjunction with graphical examination of phylogenetic distance matrices and distance frequency distribution plotting suggest the clustering of HBV genotypes into three higher-order hierarchical groups: group I, comprising genotypes A-E and G; group II, comprising genotypes F and H; and a hypothetical group III. Present-day genotype G is postulated to be a recombinant with the non-polymerase region of group III virus and the polymerase gene of an ancestral virus belonging to group I.

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Citations

Jun 22, 2012·Journal of Virology·Joshua T SchifferKeith R Jerome
Sep 7, 2013·Journal of Medical Virology·Michael O BacligFilipinas F Natividad
Feb 17, 2010·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Fuat KurbanovMasashi Mizokami
Nov 10, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Gilberto VaughanYury E Khudyakov

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