Supramolecular double-stranded Archimedean spirals and concentric toroids.

Nature Communications
Norihiko SasakiKazunori Sugiyasu

Abstract

Connecting molecular-level phenomena to larger scales and, ultimately, to sophisticated molecular systems that resemble living systems remains a considerable challenge in supramolecular chemistry. To this end, molecular self-assembly at higher hierarchical levels has to be understood and controlled. Here, we report unusual self-assembled structures formed from a simple porphyrin derivative. Unexpectedly, this formed a one-dimensional (1D) supramolecular polymer that coiled to give an Archimedean spiral. Our analysis of the supramolecular polymerization by using mass-balance models suggested that the Archimedean spiral is formed at high concentrations of the monomer, whereas other aggregation types might form at low concentrations. Gratifyingly, we discovered that our porphyrin-based monomer formed supramolecular concentric toroids at low concentrations. Moreover, a mechanistic insight into the self-assembly process permitted a controlled synthesis of these concentric toroids. This study both illustrates the richness of self-assembled structures at higher levels of hierarchy and demonstrates a topological effect in noncovalent synthesis.

References

Mar 30, 2002·Science·George M Whitesides, Bartosz Grzybowski
Jul 5, 2005·Science·Robert F Service
Feb 12, 2009·Journal of the American Chemical Society·Yiqun ZhangMinghua Liu
Sep 23, 2009·Chemical Reviews·Tom F A De GreefE W Meijer
Jan 20, 2012·Nature·Peter A KorevaarE W Meijer
Jul 20, 2012·Journal of the American Chemical Society·Peter A KorevaarE W Meijer
Aug 4, 2012·Science·Paul A RuparIan Manners
Feb 22, 2014·Nature Chemistry·Soichiro OgiMasayuki Takeuchi
Jul 17, 2014·Chemical Communications : Chem Comm·Bing LiSteven De Feyter
Feb 6, 2015·Nature Nanotechnology·Elio Mattia, Sijbren Otto
Nov 3, 2015·Cell·Nicolas ChiaruttiniAurélien Roux
Jul 7, 2016·Nature Nanotechnology·Bartosz A Grzybowski, Wilhelm T S Huck
Apr 1, 2017·Science·C Nadir KaplanL Mahadevan
May 10, 2017·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Takeshi Hasegawa
Apr 1, 2018·Nature Communications·Ananya MishraSubi J George
Jun 12, 2018·Journal of the American Chemical Society·Mathijs F J MabesooneE W Meijer
Jul 31, 2018·Journal of the American Chemical Society·Sung Ho JungKazunori Sugiyasu
Feb 21, 2019·Journal of the American Chemical Society·Anja LangenstroerGustavo Fernández
Mar 21, 2019·Journal of the American Chemical Society·Marius WehnerFrank Würthner
Mar 30, 2019·Science·Ghislaine Vantomme, E W Meijer
Jul 28, 2019·Journal of the American Chemical Society·Atsuhito SuzukiShiki Yagai
Nov 23, 2019·Accounts of Chemical Research·Huub M M Ten Eikelder, Albert J Markvoort
Dec 18, 2019·The Journal of Physical Chemistry Letters·Prithwidip SahaThiruvancheril G Gopakumar
Feb 6, 2020·Angewandte Chemie·Hans-Werner Schmidt, Frank Würthner
Mar 10, 2020·Chemistry : a European Journal·Norihiko SasakiKazunori Sugiyasu
Apr 3, 2020·Chemical Communications : Chem Comm·Takumi AizawaShiki Yagai

❮ Previous
Next ❯

Citations

Apr 30, 2021·Journal of the American Chemical Society·Jonas MaternGustavo Fernández
Jun 12, 2021·Journal of the American Chemical Society·Iván Robayo-MolinaMicheál D Scanlon
Jul 27, 2021·Journal of the American Chemical Society·Souvik SarkarSubi J George
Aug 7, 2021·Organic Chemistry Frontiers : an International Journal of Organic Chemistry·Nils BäumerGustavo Fernández

❮ Previous
Next ❯

Methods Mentioned

BETA
atomic-force microscopy
AFM
transmission
X-ray

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.