Suprathreshold excitation of frog tectal neurons by short spike trains of single retinal ganglion cell

Experimental Brain Research
Antanas KurasVaida Batuleviciene

Abstract

It has been established that coincident inputs from multiple presynaptic axons are required to achieve a suprathreshold level of excitation for the most of central neurons. The present study, however, was designed to determine whether a train of spikes of an individual retinal ganglion cell (that is, input from a single presynaptic axon) targeting a frog tectum layer F could evoke suprathreshold excitation of tectal neurons. The lungs of immobilized frog were artificially ventilated during experiments. An individual ganglion cell was electrically stimulated in the retina through a multi-channel electrode. Responses evoked in the tectum by the stimulation were recorded extracellularly from a terminal arborization of the retinotectal fiber using the carbon-fiber microelectrode. Negative and negative-positive spikes (referred to as first type population responses) and polyphasic spikes followed by excitatory synaptic potentials (referred to as second type population responses) were observed in the recordings of retinotectal activity. Usually, the population responses have ensued after the frequency facilitated first and/or second testing individual retinotectal synaptic potential and disappeared in a threshold manner with a reduct...Continue Reading

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Citations

Nov 27, 2008·Experimental Brain Research·Armantas Baginskas, Antanas Kuras
Apr 25, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Chris SekirnjakE J Chichilnisky
Jun 26, 2012·Neuroscience Letters·Armantas BaginskasAntanas Kuras
Jan 27, 2006·Journal of Neurophysiology·Chris SekirnjakE J Chichilnisky

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