PMID: 1206850Dec 1, 1975Paper

Surface areas of brush border and lateral cell walls in the rabbit proximal nephron

Kidney International
L W Welling, D J Welling

Abstract

A morphometric technique is used to estimate the absolute and relative surface areas of the brush border microvilli and cell walls bordering lateral intercellular spaces. In isolated, perfused proximal tubule from rabbit, the luminal and lateral surfaces are equal in area. For proximal convoluted tubules (PCT) each surface is 4.1 +/- 0.3 mu2/mu3 of epithelial cell volume or approximately 2.9 X 10(6) mu2/mm of tubule length. In proximal straight tubules (PST) the areas are 2.6 +/- 0.2 mu2/mu3 or 1.2 X 10(6) mu2/mm. Brush border enlarges the apical cell surface 36-fold in PCT and 15-fold in PST. The luminal and lateral cell surfaces each are approximately 20-fold (in PCT) and 10-fold (in PST) greater than the areas of the basal cell surface and tubule basement membrane. These data may be important in the context of an intercellular transport model.

References

Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·J Rostgaard, L Thuneberg
May 1, 1972·The Journal of Clinical Investigation·L W Welling, J J Grantham
Jun 1, 1966·The American Journal of Physiology·M BurgJ Orloff
Sep 1, 1967·The Journal of General Physiology·J M Diamond, W H Bossert
Jan 27, 1962·Nature·P F CURRAN, J R MACINTOSH
Dec 1, 1962·The Journal of Cell Biology·A V Loud

❮ Previous
Next ❯

Citations

Nov 1, 1984·Pflügers Archiv : European journal of physiology·E GonzálesG Whittembury
Apr 1, 1984·Pflügers Archiv : European journal of physiology·P Carpi-MedinaG Whittembury
Jul 1, 1987·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·K TiedemannP Basto
Jan 1, 1987·The Journal of Membrane Biology·M M Meyer, A S Verkman
Oct 31, 1980·The Journal of Membrane Biology·D BasmadjianA D Baines
May 15, 1981·The Journal of Membrane Biology·A M Weinstein, J L Stephenson
Aug 1, 1988·The Journal of Membrane Biology·P Carpi-MedinaG Whittembury
May 1, 1994·Bulletin of Mathematical Biology·T A KrahnA M Weinstein
Aug 1, 1979·Biophysical Journal·A M Weinstein, J L Stephenson
May 1, 1985·The Journal of General Physiology·S McLaughlin, R T Mathias
Jan 29, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Alicia A McDonough
Sep 7, 2012·American Journal of Physiology. Renal Physiology·Zhaopeng DuTong Wang
Sep 3, 2010·American Journal of Physiology. Renal Physiology·Sheldon WeinbaumAlan M Weinstein
Jun 1, 1989·The Journal of Clinical Investigation·P A Preisig, R J Alpern
Aug 5, 1998·Proceedings of the National Academy of Sciences of the United States of America·J SchnermannA S Verkman
Sep 1, 1994·Pflügers Archiv : European journal of physiology·S DijkstraR Greger
Nov 1, 1982·Kidney International·J A Schafer, D W Barfuss
Aug 1, 1986·Kidney International·G WhittemburyH Linares
Apr 18, 2008·Kidney International·Jurgen Schnermann, Josephine P Briggs
Feb 1, 1978·Kidney International·L W WellingJ J Hill
May 1, 1976·Kidney International·L W Welling, D J Welling
Sep 1, 1980·Kidney International·A RastegarJ P Hayslett
Mar 21, 1998·Toxicologic Pathology·J W Verlander
Jul 22, 1982·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·G Whittembury, B S Hill
Jun 1, 1988·Journal of Electron Microscopy Technique·L W Welling, D J Welling
May 1, 1979·The Anatomical Record·R E BulgerD C Dobyan
Feb 5, 2015·American Journal of Physiology. Renal Physiology·Zhaopeng DuTong Wang
Sep 21, 2000·American Journal of Physiology. Renal Physiology·P GuoS Weinbaum
Nov 1, 1989·The American Journal of Physiology·A S Verkman
Dec 8, 2020·American Journal of Physiology. Renal Physiology·Mathieu Lemaire
Mar 1, 1996·The American Journal of Physiology·D WellingE Wagner
Apr 14, 1986·Biochimica Et Biophysica Acta·J PratzB Corman

❮ Previous
Next ❯

Related Concepts

Related Feeds