Surface coatings to avoid dual antiplatelet therapy

Der Radiologe
Ruben Mühl-Benninghaus

Abstract

The development of microstents for aneurysm treatment has greatly expanded endovascular aneurysm therapy. Due to the increased amount of foreign material, the use of such stents is associated with an increased risk of thrombus formation and therewith the associated risk of ischemic stroke. For this reason, various surface coatings have recently been developed. The primary aim of these coatings is to reduce the foreign matter-mediated platelet adhesion to the stent surfaces. The potential reduction of dual antiplatelet therapy when using coated stents was recently discussed. But currently, no neurointerventional guidelines or recommendations endorse the stent implantation under single antiplatelet therapy. This article describes the different coatings in the field of neurointervention and their mode of action.

References

Jan 15, 2000·Journal of the American College of Cardiology·P H GreweK M Müller
Dec 5, 2009·Stroke; a Journal of Cerebral Circulation·Michel PiotinJacques Moret
Sep 16, 2016·La Radiologia medica·Mario MutoGianluigi Guarnieri
Dec 16, 2018·Journal of Neurointerventional Surgery·Nathan W ManningJason D Wenderoth
Mar 15, 2019·Cardiovascular and Interventional Radiology·Pervinder BhogalHans Henkes
Jun 30, 2019·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Hans HenkesHermann Monstadt
Aug 15, 2019·Cardiovascular and Interventional Radiology·T Lenz-HabijanH Henkes

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