Surface-enhanced Raman gene probe for HIV detection

Analytical Chemistry
N IsolaT Vo-Dinh

Abstract

We report, for the first time, the use of surface-enhanced Raman (SERS)-active labels for primers used in polymerase chain reaction amplification of specific target DNA sequences. This method has the potential for combining the spectral selectivity and high sensitivity of the SERS technique with the inherent molecular specificity offered by DNA sequence hybridization. The effectiveness of the detection scheme is demonstrated using the gag gene sequence of the human immunodeficiency virus. The potential use of multiple probes for simultaneous detection of multiple biological targets is discussed.

References

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Citations

Nov 15, 2007·Analytical and Bioanalytical Chemistry·Katharina HeringJürgen Popp
Dec 11, 2008·Analytical and Bioanalytical Chemistry·Jonathan P ScaffidiTuan Vo-Dinh
Oct 31, 2008·Talanta·D PappasJ D Winefordner
Feb 24, 2001·Biosensors & Bioelectronics·J S LundgrenF S Ligler
Jul 2, 2003·Biosensors & Bioelectronics·C Brandon DavisSara A Brazill
Sep 1, 2005·Photodiagnosis and Photodynamic Therapy·Janelle M Reyes-GoddardNicholas Stone
May 1, 2007·Analytical Chemistry·Lan SunJoseph Irudayaraj
May 24, 2013·Chemical Reviews·Halina Abramczyk, Beata Brozek-Pluska
Sep 29, 2009·The Journal of Physical Chemistry. B·Lan Sun, Joseph Irudayaraj
Nov 22, 2012·ACS Nano·Jörg BochterleAnnemarie Pucci
Apr 30, 2008·Chemical Society Reviews·Duncan Graham, Karen Faulds
Oct 19, 2005·Journal of Biomedical Optics·Shuping XuYukihiro Ozaki
May 28, 2013·Molecular Cancer·Jakub SurmackiHalina Abramczyk
Aug 7, 2013·Nanomedicine·Mark E Keating, Hugh J Byrne
Aug 25, 2007·Nanomedicine·Lin WangWeihong Tan
Mar 1, 2014·Analytical and Bioanalytical Chemistry·Xuefang GuShu Tian
Mar 16, 2013·Physical Chemistry Chemical Physics : PCCP·Hsin-Neng WangTuan Vo-Dinh
Aug 1, 2009·Expert Opinion on Drug Discovery·Tuan Vo-DinhVictoria Seewaldt
Dec 24, 2011·Bioelectrochemistry·Robert P JohnsonPhilip N Bartlett
Mar 6, 2010·Current Opinion in Biotechnology·Regina Treffer, Volker Deckert
Jun 12, 2009·Journal of Biophotonics·Tuan Vo-DinhJonathan Scaffidi
Jan 1, 2008·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Tuan Vo-Dinh
Feb 1, 2005·Biosensors & Bioelectronics·Hui PengJadranka Travas-Sejdic
Feb 13, 2007·Nanomedicine : Nanotechnology, Biology, and Medicine·Tuan Vo-DinhMusundi Wabuyele
Oct 6, 2005·Biosensors & Bioelectronics·Hui PengJadranka Travas-Sejdic
Oct 16, 2014·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Tuan Vo-DinhGuy D Griffin
Jul 13, 2006·Faraday Discussions·Anjali PalT Vo-Dinh
Sep 27, 2003·Expert Review of Molecular Diagnostics·Mustafa CulhaTuan Vo-Dinh
Jul 13, 2006·Faraday Discussions·Mino GreenTony Cass
May 12, 2015·Physical Chemistry Chemical Physics : PCCP·Sara FateixaTito Trindade
Aug 25, 2007·Applied Spectroscopy·Rebecca A JensenSteven R Emory
Apr 11, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kun GuoSuhong Chen

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